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Title: [Triple synchronous primary gynaecological tumours. A case report].
Other Titles: Tumores triple sincrónicos ginecológicos. Reporte de un caso.
Authors: Gutiérrez-Palomino, Laura
Romo-de Los Reyes, José María
Pareja-Megía, María Jesús
García-Mejido, José Antonio
Keywords: Cáncer de endometrio;Cáncer de ovario;Cáncer tubular;Endometrial cancer;Fallopian tube cancer;Multiple synchronous cancers;Neoplasias sincrónicas;Neoplasias sincrónicas múltiples;Ovarian cancer;Synchronous cancers
metadata.dc.subject.mesh: Adenocarcinoma
Carcinoma, Endometrioid
Chemotherapy, Adjuvant
Combined Modality Therapy
Fallopian Tube Neoplasms
Middle Aged
Neoplasms, Multiple Primary
Ovarian Diseases
Ovarian Neoplasms
Radiotherapy, Adjuvant
Uterine Neoplasms
Issue Date: 1-Aug-2015
Abstract: Synchronous multiple primary malignancies in the female genital tract are infrequent. From 50 to 70% of them corresponds to synchronous cancers of the endometrium and ovary. To our knowledge, this is only the third case report in the international literature of three concurrent gynaecological cancers of epithelial origin. A case is presented, as well as a literature review due to the infrequency of its diagnosis and the lack of information on the subject. A 49-year-old woman, with previous gynaecological history of ovarian endometriosis. She underwent a hysterectomy and bilateral oophorectomy, as she had been diagnosed with endometrial hyperplasia with atypia. The final histopathology reported synchronous ovarian, Fallopian tube, and endometrial cancer. An extension study and complete surgical staging was performed, both being negative. She received adjuvant treatment of chemotherapy and radiotherapy. She is currently free of disease. The aetiology is uncertain. There is controversy relating to increased susceptibility of synchronous neoplasms to pelvic endometriosis and inherited genetic syndromes. Its diagnosis needs to differentiate them from metastatic disease. Additionally, they are problematical from a clinical, diagnostic, therapeutic, and prognostic point of view. The presentation of more cases of triple synchronous cancers is necessary for a complete adjuvant and surgical treatment.
metadata.dc.identifier.doi: 10.1016/j.circir.2015.06.015
Appears in Collections:Producción 2020

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