Please use this identifier to cite or link to this item:
Title: Neuropsychiatric Symptoms in Posterior Cortical Atrophy and Alzheimer Disease.
Authors: Suárez-González, Aida
Crutch, Sebastian J
Franco-Macías, Emilio
Gil-Néciga, Eulogio
Keywords: neuropsychiatric inventory;neuropsychiatric symptoms;posterior cortical atrophy;visual hallucinations
metadata.dc.subject.mesh: Aged
Alzheimer Disease
Cerebral Cortex
Diagnosis, Differential
Irritable Mood
Lewy Body Disease
Middle Aged
Personality Inventory
Severity of Illness Index
Issue Date: 24-Sep-2015
Abstract: Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome characterized by early progressive visual dysfunction in the context of relative preservation of memory and a pattern of atrophy mainly involving the posterior cortex. The aim of the present study is to characterize the neuropsychiatric profile of PCA. The Neuropsychiatric Inventory was used to assess 12 neuropsychiatric symptoms (NPS) in 28 patients with PCA and 34 patients with typical Alzheimer disease (AD) matched by age, disease duration, and illness severity. The most commonly reported NPS in both groups were depression, anxiety, apathy, and irritability. However, aside from a trend toward lower rates of apathy in patients with PCA, there were no differences in the percentage of NPS presented in each group. All those patients presenting visual hallucinations in the PCA group also met diagnostic criteria for dementia with Lewy bodies (DLB). Auditory hallucinations were only present in patients meeting diagnosis criteria for DLB. Prevalence of the 12 NPS examined was similar between patients with PCA and AD. Hallucinations in PCA may be helpful in the differential diagnosis between PCA-AD and PCA-DLB.
metadata.dc.identifier.doi: 10.1177/0891988715606229
ISSN: 0891-9887
Appears in Collections:Producción 2020

Files in This Item:
File SizeFormat 
PMC4748542.pdf222,97 kBAdobe PDFView/Open

This item is protected by original copyright

This item is licensed under a Creative Commons License Creative Commons