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Title: Comorbidities in Patients With Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A Comparative Registries-Based Study.
Authors: Rúa-Figueroa, Iñigo
Fernández Castro, Mónica
Andreu, José L
Sanchez-Piedra, Carlos
Martínez-Taboada, Víctor
Olivé, Alejandro
López-Longo, Javier
Rosas, José
Galindo, María
Calvo-Alén, Jaime
Fernández-Nebro, Antonio
Alonso, Fernando
Rodríguez-Lozano, Beatriz
Alberto García Vadillo, Jesús
Menor, Raúl
Narváez, Francisco Javier
Erausquin, Celia
García-Aparicio, Ángel
Tomero, Eva
Manrique-Arija, Sara
Horcada, Loreto
Uriarte, Esther
Gil, Susana
Blanco, Ricardo
López-González, Ruth
Boteanu, Alina
Freire, Mercedes
Galisteo, Carlos
Rodríguez-Gómez, Manuel
Díez-Álvarez, Elvira
Pego-Reigosa, José M
Sjogrenser and Relesser Researchers and EAS-SER Group
metadata.dc.subject.mesh: Adult
Cardiovascular Diseases
Cohort Studies
Cross-Sectional Studies
Lupus Erythematosus, Systemic
Middle Aged
Sjogren's Syndrome
Issue Date: 21-Nov-2016
Abstract: To compare the prevalence of the main comorbidities in 2 large cohorts of patients with primary Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE), with a focus on cardiovascular (CV) diseases. This was a cross-sectional multicenter study where the prevalence of more relevant comorbidities in 2 cohorts was compared. Patients under followup from SJOGRENSER (Spanish Rheumatology Society Registry of Primary SS) and RELESSER (Spanish Rheumatology Society Registry of SLE), and who fulfilled the 2002 American-European Consensus Group and 1997 American College of Rheumatology classification criteria, respectively, were included. A binomial logistic regression analysis was carried out to explore potential differences, making general adjustments for age, sex, and disease duration and specific adjustments for each variable, including CV risk factors and treatments, when appropriate. A total of 437 primary SS patients (95% female) and 2,926 SLE patients (89% female) were included. The mean age was 58.6 years (interquartile range [IQR] 50.0-69.9 years) for primary SS patients and 45.1 years (IQR 36.4-56.3 years) for SLE patients (P  Primary SS patients have a consistently less serious CV comorbidity burden and a lower prevalence of severe infection than those with SLE. In contrast, their risk of lymphoma is greater.
metadata.dc.identifier.doi: 10.1002/acr.23015
Appears in Collections:Producción 2020

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