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Title: [Lixisenatide in patients with type 2 diabetes and obesity: Beyond glycaemic control].
Other Titles: Lixisenatida en pacientes con diabetes tipo 2 y obesidad: más allá del control glucémico.
Authors: Roca-Rodríguez, M Mar
Muros de Fuentes, María Teresa
Piédrola-Maroto, Gonzalo
Quesada-Charneco, Miguel
Maraver-Selfa, Silvia
Tinahones, Francisco J
Mancha-Doblas, Isabel
Keywords: Análogos de GLP-1;Control metabólico;Diabetes tipo2;GLP-1;Lixisenatida;Lixisenatide;Metabolic control;Obesidad;Obesity;Type 2 diabetes
metadata.dc.subject.mesh: Adult
Blood Glucose
Diabetes Mellitus, Type 2
Hypoglycemic Agents
Middle Aged
Prospective Studies
Issue Date: 22-Sep-2016
Abstract: To evaluate tolerance to lixisenatide and its effects on weight and metabolic control in type2 diabetes and obese patients. Prospective study. Endocrinology clinics in Almeria, Granada and Malaga. Patients with type2 diabetes and obesity. Response and tolerance to lixisenatide treatment. Clinical and analytical data of the subjects were evaluated at baseline and after treatment. The study included 104 patients (51% women) with type2 diabetes and obesity (Almeria 18.3%; Granada 40.4%; Malaga 41.3%). The mean age was 58.4±10.5years, and the mean duration of diabetes was 11.2±6.7years. The patients were re-evaluated at 3.8±1.6months after treatment with lixisenatide. Significant improvements were found in weight (P Lixisenatide achieved significant improvements in anthropometric parameters, glycaemic control (fasting glucose and HbA1c), blood pressure and lipids. It was safe and well tolerated in most patients. In addition, there was a significant increase in the use of antihypertensive and lipid-lowering therapy.
metadata.dc.identifier.doi: 10.1016/j.aprim.2016.06.009
Appears in Collections:Producción 2020

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