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Title: Lung Cancer in Women with a Family History of Cancer: The Spanish Female-specific Database WORLD07.
Authors: Isla, Dolores
Felip, Enriqueta
Viñolas, Nuria
Provencio, Mariano
Majem, Margarita
Artal, Angel
Bover, Isabel
Lianes, Pilar
DE Las Peñas, Ramón
Catot, Silvia
DE Castro, Javier
Blasco, Ana
Terrasa, Josefa
Gonzalez-Larriba, José Luis
Juan, Oscar
Dómine, Manuel
Bernabe, Reyes
Garrido, Pilar
Keywords: Cancer;Spanish women;WORLD07 database;epidermal growth factor receptor;family history;lung cancer risk;menopausal status;smoking
metadata.dc.subject.mesh: Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
ErbB Receptors
Genetic Predisposition to Disease
Lung Neoplasms
Issue Date: 2016
Abstract: The WORLD07 project is a female-specific database to prospectively analyze the characteristics of Spanish women with lung cancer. We analyzed and compared lung cancer features in women with and without a family history of cancer/lung cancer. Two thousand and sixty women were included: 876 had a family history of cancer (lung cancer, 34%) and 886 did not, with no significant differences between groups, except for smoking status (p=0.036). We found statistically significant correlations between epidermal growth factor receptor (EGFR) mutation and smoking status in patients with a family history of cancer (r=-0.211; p Among Spanish women with lung cancer, a greater proportion were current smokers in those with a family history of cancer/lung cancer. There was a significant correlation between the presence of EGFR mutation and smoking.
metadata.dc.identifier.doi: 10.21873/anticanres.11273
Appears in Collections:Producción 2020

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