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http://hdl.handle.net/10668/10673| Title: | Salvage Therapy with Ceftolozane-Tazobactam for Multidrug-Resistant Pseudomonas aeruginosa Infections. |
| Authors: | Castón, Juan José De la Torre, Álvaro Ruiz-Camps, Isabel Sorlí, María Luisa Torres, Vicente Torre-Cisneros, Julián |
| Keywords: | Pseudomonas aeruginosa;ceftolozane-tazobactam;salvage therapy |
| metadata.dc.subject.mesh: | Adult Aged Anti-Bacterial Agents Cephalosporins Drug Resistance, Multiple, Bacterial Female Humans Male Microbial Sensitivity Tests Middle Aged Penicillanic Acid Pneumonia, Bacterial Pseudomonas Infections Pseudomonas aeruginosa Retrospective Studies Salvage Therapy Shock, Septic Survival Analysis Tazobactam |
| Issue Date: | 23-Feb-2017 |
| Abstract: | Infections caused by multidrug-resistant Pseudomonas aeruginosa (MDRPA) present a major problem for therapeutic management. We report here our experience with 12 patients with a severe MDRPA infection (6 of which were pneumonia) who received salvage therapy with ceftolozane-tazobactam after inappropriate empirical treatment and/or suboptimal targeted treatment. Although 10 of the 12 patients (83.3%) experienced septic shock, only 3 patients (25%) died during the follow-up period. Microbiological cure in 7 patients (58.3%) was observed. |
| URI: | http://hdl.handle.net/10668/10673 |
| metadata.dc.identifier.doi: | 10.1128/AAC.02136-16 |
| Appears in Collections: | Producción 2020 |
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