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Title: Severe thrombocytopenia induced by iodinated contrast after coronary angiography: The use of gadolinium contrast and intravascular ultrasound as an alternative to guide percutaneous coronary intervention.
Authors: Cubero-Gómez, José María
Guerrero Márquez, Francisco J
Diaz-de la-Llera, Luis
Fernández-Quero, Mónica
Guisado-Rasco, Agustín
Villa-Gil-Ortega, Manuel
Keywords: Agentes de contraste;Contrast agents;Ecografia intracoronária;Imagem;Imaging;Intervenção copronária percutânea;Intravascular ultrasound;Percutaneous coronary intervention
metadata.dc.subject.mesh: Contrast Media
Coronary Angiography
Heterocyclic Compounds
Iodine Compounds
Ioxaglic Acid
Middle Aged
Organometallic Compounds
Percutaneous Coronary Intervention
Severity of Illness Index
Surgery, Computer-Assisted
Ultrasonography, Interventional
Issue Date: 14-Dec-2016
Abstract: Acute contrast-induced thrombocytopenia is a rare event with the use of modern low osmolarity iodinated contrast media. The pathophysiological mechanism that causes platelet counts to drop has not been identified, but an immunological mechanism is suspected due to cytotoxicity after previous exposure to contrast. We report the case of a 47-year-old male patient with acute severe thrombocytopenia due to iodinated contrast media exposure. His platelet count after the procedure with the highest amount of contrast was zero, which is the lowest reported platelet count to date. Percutaneous coronary revascularization under both intravascular ultrasound and gadolinium contrast guidance was performed without complications. The most feared complication after the use of gadolinium is nephrogenic systemic fibrosis, especially in patients on hemodialysis.
metadata.dc.identifier.doi: 10.1016/j.repc.2016.04.014
Appears in Collections:Producción 2020

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