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Title: Risk factors for excess mortality in adults with congenital heart diseases.
Authors: Oliver, Jose Maria
Gallego, Pastora
Gonzalez, Ana Elvira
Garcia-Hamilton, Diego
Avila, Pablo
Yotti, Raquel
Ferreira, Ignacio
Fernandez-Aviles, Francisco
Keywords: Adult congenital heart disease;Congenital;Excess mortality;Follow-up studies;Heart defects;Risk factors for death
metadata.dc.subject.mesh: Adolescent
Epidemiologic Methods
Heart Defects, Congenital
Middle Aged
Sex Distribution
Young Adult
Issue Date: 2017
Abstract: To examine factors related to excess mortality in a cohort of adults with congenital heart disease (CHD). We conducted a survival analysis using prospective data of 3311 adults with CHD [50.5% males, median age at entry 22.5 years (IQR 18-39), median follow-up time 10.5 years (IQR: 4.4-18)]. Survival status of each patient was further verified by cross checking with the Spanish National Death Index. During a total follow-up of 37608 person-years, 336 (10%) patients died. Annual death rate was 0.89% and standardized mortality ratio (SMR) 2.64 [95% confidence interval (CI) 2.3-3.0; P  Clinical parameters, such as anatomical features, haemodynamic sequelae, or acquired complications, were independent predictors of excess mortality in adults with CHD. Survival of individuals with no risk factors did not differ from the reference population.
metadata.dc.identifier.doi: 10.1093/eurheartj/ehw590
Appears in Collections:Producción 2020

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