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Title: Rationale and design of a multicenter, international and collaborative Coronary Artery Aneurysm Registry (CAAR).
Authors: Núñez-Gil, Iván J
Nombela-Franco, Luis
Bagur, Rodrigo
Bollati, Mario
Cerrato, Enrico
Alfonso, Emilio
Liebetrau, Christoph
De la Torre Hernandez, José María
Camacho, Benjamín
Mila, Rafael
Amat-Santos, Ignacio J
Alfonso, Fernando
Rodríguez-Olivares, Ramón
Camacho Freire, Santiago J
Lozano, Íñigo
Jiménez Díaz, Víctor Alfonso
Piraino, Davide
Latini, Roberto Adriano
Feltes, Gisela
Linares, Jose Antonio
Mancone, Massimo
Ielasi, Alfonso
Sánchez-Grande Flecha, Alejandro
Fernández Cisnal, Agustín
Ugo, Fabrizio
Jiménez Mazuecos, Jesús M
Omedè, Pierluigi
Pavani, Marco
Villablanca, Pedro A
Louka, Boshra F
Fernández-Ortiz, Antonio
CAAR Investigators
Keywords: CAAR;Coronary Aneurysm;Epidemiology;Prognosis;Registry
metadata.dc.subject.mesh: Cooperative Behavior
Coronary Aneurysm
Coronary Angiography
International Cooperation
Predictive Value of Tests
Research Design
Risk Factors
Time Factors
United States
Issue Date: 24-Mar-2017
Abstract: Coronary artery aneurysm is defined as a coronary dilation that exceeds the diameter of adjacent segments or the diameter of the patient's largest normal coronary vessel by 1.5×. It is an uncommon disease that has been diagnosed with increasing frequency since the widespread appearance of coronary angiography. The published incidence varies from 1.5% to 5%, suggesting male dominance and a predilection for the right coronary artery. Although several causes have been described, atherosclerosis accounts for ≥50% of coronary aneurysms in adults. Reported complications include thrombosis and distal embolization, rupture, and vasospasm, causing ischemia, heart failure, or arrhythmias. The natural history and prognosis remain unknown, as definitive data are scarce. Controversies persist regarding the use of medical management (antithrombotic therapy) or interventional/surgical procedures. Only some case reports or small case series are available about this condition. The Coronary Artery Aneurysm Registry (CAAR; NCT02563626) is a multicenter international ambispective registry that aims to provide insights on anatomic, epidemiologic, and clinical aspects of this substantially unknown entity. In addition, the registry will assess management strategies (conservative, interventional, or surgical) and their short- and long-term results in a large cohort of patients. Unique identifier: NCT02563626.
metadata.dc.identifier.doi: 10.1002/clc.22705
Appears in Collections:Producción 2020

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