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dc.contributor.authorRojas, Pilar
dc.contributor.authorFriaza, Vicente
dc.contributor.authorGarcía, Elisa
dc.contributor.authorde la Horra, Carmen
dc.contributor.authorVargas, Sergio L
dc.contributor.authorCalderón, Enrique J
dc.contributor.authorPavón, Antonio
dc.description.abstractPneumocystis pneumonia is a well-recognized lung disease of premature and malnourished babies. Even though serologic studies have shown that children are exposed to Pneumocystis jirovecii early in life, the epidemiology of human P. jirovecii infection and the host-microorganism relationship in infancy remain poorly understood. The aim of the present study was to investigate the prevalence of P. jirovecii colonization in preterm infants and its possible association with medical complications. A prospective observational study of preterm infants (birth weight A total of 128 preterm infants were included during the study period. Pneumocystis DNA was identified in 25.7% (95% confidence interval [CI], 17.8%-33.7%) of newborns studied. A significant increase of respiratory distress syndrome in colonized group, even after adjusting for confounding factors (odds ratio, 2.7 [95% CI, 1.0-7.5]; P = .04), was observed. No differences were observed in other medical conditions between the 2 groups. Pneumocystis jirovecii colonization is frequent in preterm births and could be a risk factor to develop respiratory distress syndrome among preterm infants.
dc.subjectpreterm infants
dc.subjectrespiratory distress syndrome
dc.subject.meshBirth Weight
dc.subject.meshCarrier State
dc.subject.meshDNA, Fungal
dc.subject.meshGestational Age
dc.subject.meshInfant, Newborn
dc.subject.meshInfant, Premature
dc.subject.meshPneumocystis carinii
dc.subject.meshPneumonia, Pneumocystis
dc.subject.meshProspective Studies
dc.subject.meshRespiratory Distress Syndrome, Newborn
dc.titleEarly Acquisition of Pneumocystis jirovecii Colonization and Potential Association With Respiratory Distress Syndrome in Preterm Newborn Infants.
dc.typeresearch article
dc.rights.accessRightsopen access
dc.journal.titleClinical infectious diseases : an official publication of the Infectious Diseases Society of America
dc.journal.titleabbreviationClin Infect Dis
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.organizationHospital Universitario Virgen del Rocío
dc.organizationHospital Universitario Virgen del Rocío
dc.pubmedtypeJournal Article
dc.pubmedtypeObservational Study
Appears in Collections:Producción 2020

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