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Title: Consumption of fruits, vegetables and fruit juices and differentiated thyroid carcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Authors: Zamora-Ros, Raul
Béraud, Virginie
Franceschi, Silvia
Cayssials, Valerie
Tsilidis, Konstantinos K
Boutron-Ruault, Marie-Christine
Weiderpass, Elisabete
Overvad, Kim
Tjønneland, Anne
Eriksen, Anne K
Bonnet, Fabrice
Affret, Aurélie
Katzke, Verena
Kühn, Tilman
Boeing, Heiner
Trichopoulou, Antonia
Valanou, Elisavet
Karakatsani, Anna
Masala, Giovanna
Grioni, Sara
Santucci de Magistris, Maria
Tumino, Rosario
Ricceri, Fulvio
Skeie, Guri
Parr, Christine L
Merino, Susana
Salamanca-Fernández, Elena
Chirlaque, Maria-Dolores
Ardanaz, Eva
Amiano, Pilar
Almquist, Martin
Drake, Isabel
Hennings, Joakim
Sandström, Maria
Bueno-de-Mesquita, H B As
Peeters, Petra H
Khaw, Kay-Thee
Wareham, Nicholas J
Schmidt, Julie A
Perez-Cornago, Aurora
Aune, Dagfinn
Riboli, Elio
Slimani, Nadia
Scalbert, Augustin
Romieu, Isabelle
Agudo, Antonio
Rinaldi, Sabina
Keywords: EPIC;fruit juices;fruits;intake;thyroid cancer;vegetables
metadata.dc.subject.mesh: Adult
Cohort Studies
Diet, Healthy
Fruit and Vegetable Juices
Middle Aged
Prospective Studies
Thyroid Neoplasms
Issue Date: 24-Jul-2017
Abstract: Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid cancer (TC). The purpose of this study is to examine the association between the consumption of fruits, vegetables, fruit juices and differentiated thyroid cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The EPIC study is a cohort including over half a million participants, recruited between 1991 and 2000. During a mean follow-up of 14 years, 748 incident first primary differentiated TC cases were identified. F&V and fruit juice intakes were assessed through validated country-specific dietary questionnaires. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models adjusted for potential confounding factors. Comparing the highest versus lowest quartile of intake, differentiated TC risk was not associated with intakes of total F&V (HR: 0.89; 95% CI: 0.68-1.15; p-trend = 0.44), vegetables (HR: 0.89; 95% CI: 0.69-1.14; p-trend = 0.56), or fruit (HR: 1.00; 95% CI: 0.79-1.26; p-trend = 0.64). No significant association was observed with any individual type of vegetable or fruit. However, there was a positive borderline trend with fruit juice intake (HR: 1.23; 95% CI: 0.98-1.53; p-trend = 0.06). This study did not find any significant association between F&V intakes and differentiated TC risk; however a positive trend with fruit juice intake was observed, possibly related to its high sugar content.
metadata.dc.identifier.doi: 10.1002/ijc.30880
Appears in Collections:Producción 2020

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