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Title: Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study.
Authors: Gunter, Marc J
Murphy, Neil
Cross, Amanda J
Dossus, Laure
Dartois, Laureen
Fagherazzi, Guy
Kaaks, Rudolf
Kühn, Tilman
Boeing, Heiner
Aleksandrova, Krasimira
Tjønneland, Anne
Olsen, Anja
Overvad, Kim
Larsen, Sofus Christian
Redondo Cornejo, Maria Luisa
Agudo, Antonio
Sánchez Pérez, María José
Altzibar, Jone M
Navarro, Carmen
Ardanaz, Eva
Khaw, Kay-Tee
Butterworth, Adam
Bradbury, Kathryn E
Trichopoulou, Antonia
Lagiou, Pagona
Trichopoulos, Dimitrios
Palli, Domenico
Grioni, Sara
Vineis, Paolo
Panico, Salvatore
Tumino, Rosario
Bueno-de-Mesquita, Bas
Siersema, Peter
Leenders, Max
Beulens, Joline W J
Uiterwaal, Cuno U
Wallström, Peter
Nilsson, Lena Maria
Landberg, Rikard
Weiderpass, Elisabete
Skeie, Guri
Braaten, Tonje
Brennan, Paul
Licaj, Idlir
Muller, David C
Sinha, Rashmi
Wareham, Nick
Riboli, Elio
metadata.dc.subject.mesh: Adult
Cardiovascular Diseases
Cause of Death
Cerebrovascular Disorders
Digestive System Diseases
Liver Function Tests
Middle Aged
Ovarian Neoplasms
Proportional Hazards Models
Prospective Studies
Risk Factors
Issue Date: 11-Jul-2017
Abstract: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Prospective cohort study. 10 European countries. 521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition). Hazard ratios (HRs) and 95% CIs estimated using multivariable Cox proportional hazards models. The association of coffee consumption with serum biomarkers of liver function, inflammation, and metabolic health was evaluated in the EPIC Biomarkers subcohort (n = 14 800). During a mean follow-up of 16.4 years, 41 693 deaths occurred. Compared with nonconsumers, participants in the highest quartile of coffee consumption had statistically significantly lower all-cause mortality (men: HR, 0.88 [95% CI, 0.82 to 0.95]; P for trend  Reverse causality may have biased the findings; however, results did not differ after exclusion of participants who died within 8 years of baseline. Coffee-drinking habits were assessed only once. Coffee drinking was associated with reduced risk for death from various causes. This relationship did not vary by country. European Commission Directorate-General for Health and Consumers and International Agency for Research on Cancer.
metadata.dc.identifier.doi: 10.7326/M16-2945
Appears in Collections:Producción 2020

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