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Title: Clinical Impact of Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement.
Authors: Auffret, Vincent
Webb, John G
Eltchaninoff, Hélène
Muñoz-García, Antonio J
Himbert, Dominique
Tamburino, Corrado
Nombela-Franco, Luis
Nietlispach, Fabian
Morís, César
Ruel, Marc
Dager, Antonio E
Serra, Vicenç
Cheema, Asim N
Amat-Santos, Ignacio J
de Brito, Fábio Sandoli
Lemos, Pedro Alves
Abizaid, Alexandre
Sarmento-Leite, Rogério
Dumont, Eric
Barbanti, Marco
Durand, Eric
Alonso Briales, Juan H
Vahanian, Alec
Bouleti, Claire
Immè, Sebastiano
Maisano, Francesco
Del Valle, Raquel
Benitez, Luis Miguel
García Del Blanco, Bruno
Puri, Rishi
Philippon, François
Urena, Marina
Rodés-Cabau, Josep
Keywords: outcomes;permanent pacemaker implantation;right bundle branch block;sudden cardiac death;transcatheter aortic valve replacement
metadata.dc.subject.mesh: Aged
Aged, 80 and over
Aortic Valve
Aortic Valve Stenosis
Bundle-Branch Block
Cause of Death
Death, Sudden, Cardiac
Kaplan-Meier Estimate
Multivariate Analysis
Proportional Hazards Models
Risk Factors
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
Issue Date: 19-Jul-2017
Abstract: This study sought to assess the influence of baseline right bundle branch block (RBBB) on all-cause and cardiovascular mortality as well as sudden cardiac death (SCD) among patients undergoing transcatheter aortic valve replacement (TAVR). Few data exist regarding the late clinical impact of pre-existing RBBB in TAVR recipients. A total of 3,527 patients (mean age 82 ± 8 years, 50.1% men) were evaluated according to the presence of RBBB on baseline electrocardiography. Intraventricular conduction abnormalities were classified according to the American Heart Association, American College of Cardiology Foundation, and Heart Rhythm Society recommendations for standardization and interpretation of the electrocardiogram. TAVR complications and causes of death were defined according to Valve Academic Research Consortium 2 definitions. RBBB was present on baseline electrocardiography in 362 patients (10.3%) and associated with higher 30-day rates of permanent pacemaker implantation (PPI) (40.1% vs. 13.5%; p  Pre-existing RBBB was found in 10% of TAVR recipients and was associated with poorer clinical outcomes. Patients with baseline RBBB without permanent pacemakers at hospital discharge may be at especially high risk for high-degree atrioventricular block and/or SCD during follow-up. Future studies should evaluate strategies aimed at the early detection of patients at risk for late development of high-degree atrioventricular block.
metadata.dc.identifier.doi: 10.1016/j.jcin.2017.05.030
Appears in Collections:Producción 2020

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