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Title: Infective endocarditis in patients with cancer: a consequence of invasive procedures or a harbinger of neoplasm?: A prospective, multicenter cohort.
Authors: Fernández-Cruz, Ana
Muñoz, Patricia
Sandoval, Carmen
Fariñas, Carmen
Gutiérrez-Cuadra, Manuel
Pericás Pulido, Juan M
Miró, José M
Goenaga-Sánchez, Miguel Á
de Alarcón, Arístides
Bonache-Bernal, Francisco
Rodríguez, MªÁngeles
Noureddine, Mariam
Bouza Santiago, Emilio
Spanish Collaboration on Endocarditis (GAMES)
metadata.dc.subject.mesh: Aged
Cross Infection
Hospital Mortality
Middle Aged
Prospective Studies
Risk Factors
Sex Factors
Issue Date: 2017
Abstract: The aim of the study was to draw a comparison between the characteristics of infective endocarditis (IE) in patients with cancer and those of IE in noncancer patients.Patients with IE, according to the modified Duke criteria, were prospectively included in the GAMES registry between January 2008 and February 2014 in 30 hospitals. Patients with active cancer were compared with noncancer patients.During the study period, 161 episodes of IE fulfilled the inclusion criteria. We studied 2 populations: patients whose cancer was diagnosed before IE (73.9%) and those whose cancer and IE were diagnosed simultaneously (26.1%). The latter more frequently had community-acquired IE (67.5% vs 26.4%, P 
metadata.dc.identifier.doi: 10.1097/MD.0000000000007913
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