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Title: Consumption of orange fermented beverage improves antioxidant status and reduces peroxidation lipid and inflammatory markers in healthy humans.
Authors: Escudero-López, Blanca
Ortega, Ángeles
Cerrillo, Isabel
Rodríguez-Griñolo, María-Rosario
Muñoz-Hernández, Rocío
Macher, Hada C
Martín, Franz
Hornero-Méndez, Dámaso
Mena, Pedro
Del Rio, Daniele
Fernández-Pachón, María-Soledad
Keywords: antioxidant status;bioactive compounds;healthy humans;inflammation status;lipid peroxidation;orange fermented beverage
metadata.dc.subject.mesh: Adult
C-Reactive Protein
Citrus sinensis
Fruit and Vegetable Juices
Healthy Volunteers
Lipid Peroxidation
Lipoproteins, LDL
Middle Aged
Oxidative Stress
Thiobarbituric Acid Reactive Substances
Issue Date: 28-Nov-2017
Abstract: Alcoholic fermentation of fruits has generated novel products with high concentrations of bioactive compounds and moderate alcohol content. The aim of this study was to evaluate the potential effect on cardiovascular risk factors of the regular consumption by healthy humans of a beverage obtained by alcoholic fermentation and pasteurization of orange juice. Thirty healthy volunteers were enrolled in a randomized controlled study. The experimental group (n = 15) drank 500 mL orange beverage (OB) per day for 2 weeks (intervention phase), followed by a 3-week washout phase. Blood samples were collected at baseline (E-T0) and at the end of the intervention (E-T1) and washout (E-T2) phases. Controls (n = 15) did not consume OB during a 2-week period. OB intake significantly increased oxygen radical absorbance capacity (43.9%) and reduced uric acid (-8.9%), catalase (CAT) (-23.2%), thiobarbituric acid reactive substances (TBARS) (-30.2%) and C-reactive protein (-2.1%) (E-T1 vs. E-T0). These effects may represent longer-term benefits, given the decreased uric acid (-8.9%), CAT (-34.6%), TBARS (-48.4%) and oxidized low-density lipoprotein (-23.9%) values recorded after the washout phase (E-T2 vs. E-T0). The regular consumption of OB improved antioxidant status and decreased inflammation state, lipid peroxidation and uric acid levels. Thus OB may protect the cardiovascular system in healthy humans and be considered a novel functional beverage. © 2017 Society of Chemical Industry.
metadata.dc.identifier.doi: 10.1002/jsfa.8774
Appears in Collections:Producción 2020

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