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Title: Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures.
Authors: Pibarot, Philippe
Simonato, Matheus
Barbanti, Marco
Linke, Axel
Kornowski, Ran
Rudolph, Tanja
Spence, Mark
Moat, Neil
Aldea, Gabriel
Mennuni, Marco
Iadanza, Alessandro
Amrane, Hafid
Gaia, Diego
Kim, Won-Keun
Napodano, Massimo
Baumbach, Hardy
Finkelstein, Ariel
Kobayashi, Junjiro
Brecker, Stephen
Don, Creighton
Cerillo, Alfredo
Unbehaun, Axel
Attias, David
Nejjari, Mohammed
Jones, Noah
Fiorina, Claudia
Tchetche, Didier
Philippart, Raphael
Spargias, Konstantinos
Hernandez, Jose-Maria
Latib, Azeem
Dvir, Danny
Keywords: prosthesis-patient-mismatch;transcatheter aortic valve replacement;valve-in-valve
metadata.dc.subject.mesh: Aged
Aged, 80 and over
Aortic Valve
Aortic Valve Insufficiency
Aortic Valve Stenosis
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Prosthesis Design
Prosthesis Failure
Risk Assessment
Risk Factors
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome
Issue Date: 2018
Abstract: The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size). Transcatheter ViV implantation is an alternative for the treatment of patients with degenerated bioprostheses. Small label size of the surgical valve has been associated with increased mortality after ViV implantation. Data from 1,168 patients included in the VIVID (Valve-in-Valve International Data) registry were analyzed. Pre-existing PPM of the surgical valve was determined using a reference value of effective orifice area for each given model and size of implanted prosthetic valve indexed for body surface area. Severe PPM was defined according to the criteria proposed by the Valve Academic Research Consortium 2: indexed effective orifice area  Among the 1,168 patients included in the registry, 89 (7.6%) had pre-existing severe PPM. Patients with severe PPM had higher 30-day (10.3%, p = 0.01) and 1-year (unadjusted: 28.6%, p  Pre-existing PPM of the failed surgical valve is strongly and independently associated with increased risk for mortality following ViV implantation.
metadata.dc.identifier.doi: 10.1016/j.jcin.2017.08.039
Appears in Collections:Producción 2020

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