Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/1270
Title: Transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves: Results from the global valve-in-valve registry.
Authors: Dvir, Danny
Webb, John
Brecker, Stephen
Bleiziffer, Sabine
Hildick-Smith, David
Colombo, Antonio
Descoutures, Fleur
Hengstenberg, Christian
Moat, Neil E
Bekeredjian, Raffi
Napodano, Massimo
Testa, Luca
Lefevre, Thierry
Guetta, Victor
Nissen, Henrik
Hernández, José-María
Roy, David
Teles, Rui C.
Segev, Amit
Dumonteil, Nicolas
Fiorina, Claudia
Gotzmann, Michael
Tchetche, Didier
Abdel-Wahab, Mohamed
Marco, Federico de
Baumbach, Andreas
Laborde, Jean-Claude
Kornowski, Ran
metadata.dc.contributor.authoraffiliation: [Dvir,D] Washington Hospital Center, Washington, USA. [Dvir,D; Kornowski,R] Rabin Medical Center and Tel-Aviv University, Tel-Aviv, Israel. [Webb,J] St. Paul's Hospital, Vancouver, British Columbia, Canada. [Brecker,S; Roy,D; Laborde,JC] St. George's Hospital, London, United Kingdom. [Bleiziffer,S] German Heart Center, Munich, Germany. [Hildick-Smith,D] Sussex Cardiac Centre, Brighton, UK. [Colombo,A] San Raffaele Scientific Institute, Milan, Italy. [Descoutures,F] Hospital Bichat, Paris, France. [Hengstenberg,C] Universitaetsklinikum Regensburg, Regensburg, Germany. [Moat,NE] Royal Brompton Hospital, London, United Kingdom. [Bekeredjian,R] University of Heidelberg, Heidelberg, Germany. [Napodano,M] Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova, Padova, Italy. [Testa,L] Clinical Institute S. Ambrogio, Milan, Italy. [Lefevre,T] Hopital Jacques Cartier, Massy, France. [Guetta,V; Sergev,A] Sheba Medical Center, Tel Hashomer, Israel. [Nissen,H] Odense University Hospital, Odense, Denmark. [Hernández,JM] Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Teles,RC] Hospital de Santa Cruz, Lisboa, Portugal. [Dumonteil,N] Rangueil University Hospital, Toulouse, France. [Fiorina,C] Azienda Ospedaliere Spedali Civili di Brescia, Brescia, Italy. [Gotzmann,M] Bergmannsheil Ruhr University, Bochum, Germany. [Tchetche,D] Clinique Pasteur, Toulouse, France. [Abdel-Wahab,M] Segeberger Kliniken GmbH, Bad Segeberg, Germany. [De Marco,F] Ospedale Niguarda Ca' Granda, Milan, Italy. [Baumbach,A] Bristol Heart Institute, Bristol, United Kingdom.
Keywords: Insuficiencia de la Válvula Aórtica;Estenosis de la Válvula Aórtica;Enfermedad de la Arteria Coronaria;Implantación de Prótesis de Válvulas Cardíacas;Prótesis Valvulares Cardíacas;Cateterismo Venoso Central;Resultado del Tratamiento;Bioprosthesis;Transcatheter aortic valve implantation;Valve-in-valve
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Aortic Valve Insufficiency
Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Aortic Valve Stenosis
Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Arterial Occlusive Diseases::Arteriosclerosis::Coronary Artery Disease
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Cardiac Surgical Procedures
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Prostheses and Implants::Heart Valve Prosthesis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Vascular Surgical Procedures::Endovascular Procedures::Catheterization, Central Venous
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Prostheses and Implants::Bioprosthesis
Issue Date: 6-Nov-2012
Publisher: American Heart Association
Citation: Dvir D, Webb J, Brecker S, Bleiziffer S, Hildick-Smith D, Colombo A, et al. Transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves: Results from the global valve-in-valve registry. Circulation. 2012; 126(19):2335-2344
Abstract: BACKGROUND Transcatheter aortic valve-in-valve implantation is an emerging therapeutic alternative for patients with a failed surgical bioprosthesis and may obviate the need for reoperation. We evaluated the clinical results of this technique using a large, worldwide registry. METHODS AND RESULTS The Global Valve-in-Valve Registry included 202 patients with degenerated bioprosthetic valves (aged 77.7±10.4 years; 52.5% men) from 38 cardiac centers. Bioprosthesis mode of failure was stenosis (n=85; 42%), regurgitation (n=68; 34%), or combined stenosis and regurgitation (n=49; 24%). Implanted devices included CoreValve (n=124) and Edwards SAPIEN (n=78). Procedural success was achieved in 93.1% of cases. Adverse procedural outcomes included initial device malposition in 15.3% of cases and ostial coronary obstruction in 3.5%. After the procedure, valve maximum/mean gradients were 28.4±14.1/15.9±8.6 mm Hg, and 95% of patients had ≤+1 degree of aortic regurgitation. At 30-day follow-up, all-cause mortality was 8.4%, and 84.1% of patients were at New York Heart Association functional class I/II. One-year follow-up was obtained in 87 patients, with 85.8% survival of treated patients. CONCLUSIONS The valve-in-valve procedure is clinically effective in the vast majority of patients with degenerated bioprosthetic valves. Safety and efficacy concerns include device malposition, ostial coronary obstruction, and high gradients after the procedure.
Description: Journal Article."Comment in Valvular disease: Aortic valve-in-valve replacement. [Nat Rev Cardiol. 2012] Valve in valve: another milestone for transcatheter valve therapy. [Circulation. 2012]". (Nota tomada de PubMed)
URI: http://hdl.handle.net/10668/1270
metadata.dc.relation.publisherversion: http://circ.ahajournals.org/content/126/19/2335
metadata.dc.identifier.doi: 10.1161/CIRCULATIONAHA.112.104505
ISSN: 1524-4539 (Online)
0009-7322 (Print)
Appears in Collections:01- Artículos - Hospital Virgen de la Victoria

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