Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/1316
Title: Effect of iodine prophylaxis during pregnancy on neurocognitive development of children during the first two years of life.
Authors: Velasco, Ines
Carreira, Monica
Santiago, Piedad
Muela, José Antonio
García-Fuentes, Eduardo
Sánchez-Muñoz, Baltasar
Garriga, Maria J
González-Fernández, Maria C
Rodríguez, Alvaro
Caballero, Francisco F
Machado, Alberto
González-Romero, Stella
Anarte, Maria T
Soriguer, Federico
metadata.dc.contributor.authoraffiliation: [Velasco,I] Hospital La Merced, Osuna, Spain. [Carreira,M; Caballero,FF; Anarte,MT] Facultad de Psicología, Universidadde Málaga, Málaga, Spain. [Santiago,P] Servicio de Endocrinología y Nutrición, Hospital General, Jaén, Spain. [Muela,JA; Rodríguez,A] Facultad de Humanidades y Ciencias de la Educación, Departamento de Psicología, Universidad de Jaén, Jaén, Spain. [García-Fuentes,E] Fundación Imabis, Málaga, Spain. Centro de Investigación Biomédica en Red de Fisiopatología Obesidad y Nutrición, ISCIII, Málaga, Spain. [Sánchez-Muñoz,B] Laboratorio de Análisis Clínicos, Hospital General, Jaén, Spain. [Garriga,MJ] Laboratorio de Hormonas, Hospital Universitario Carlos Haya, Málaga, Spain. [González-Fernandez,MC] Unidad de Investigación, Hospital la Merced, Osuna, Spain. [Machado,A] Hospital Punta de Europa de Algeciras, Cádiz, Spain. [González-Romero,S; Soriguer,F] Servicio de Endocrinología y Nutrición, Hospital Universitario Carlos Haya, Málaga, Spain. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Málaga, Spain.
Keywords: Suplementos Dietéticos;Cognición;Embarazo;Yodo;Glándula Tiroides;Hormonas tiroideas
metadata.dc.subject.mesh: Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Human Development::Child Development
Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition
Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Supplements
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Infant
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Halogens::Iodine
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy
Medical Subject Headings::Anatomy::Endocrine System::Endocrine Glands::Thyroid Gland
Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Thyroid Hormones
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Issue Date: Sep-2009
Publisher: Endocrine Society
Citation: Velasco I, Carreira M, Santiago P, Muela JA, García-Fuentes E, Sánchez-Muñoz B, et al. Effect of iodine prophylaxis during pregnancy on neurocognitive development of children during the first two years of life. J. Clin. Endocrinol. Metab.. 2009; 94(9):3234-41
Abstract: CONTEXT The association between thyroid function during pregnancy and the later mental and psychomotor development of the child is supported by numerous experimental, clinical, and epidemiological studies. OBJECTIVE The aim of the study was to evaluate the psychological development of infants aged 3 to 18 months whose mothers had received 300 microg of potassium iodide during the first trimester of their pregnancy and compare with infants whose mothers had received no iodine supplements. DESIGN AND STUDY SUBJECTS: The study included 133 women who had received 300 microg of potassium iodine and 61 women who had received no iodine supplements. MAIN OUTCOME MEASURES The neuropsychological status of the children was evaluated with the Bayley Scales of Infant Development, and measurements were made of TSH, free T(3), free T(4), and urinary iodine. RESULTS Those children whose mothers had received an iodine supplement of 300 microg had a more favorable psychometric assessment than those of the other group of mothers. They had higher scores on the Psychomotor Development Index (P = 0.02) and the Behavior Rating Scale. CONCLUSIONS Dietary iodine supplements not only have no harmful effect on the neurodevelopment of the children, they may even be beneficial. Given the possible presence of confounding variables not controlled for in this study, these findings should be considered as preliminary.
Description: Journal Article; Research Support, Non-U.S. Gov't; "Comment in: What do we know about iodine supplementation in pregnancy? [J Clin Endocrinol Metab. 2009]" (Nota tomada de PubMed).
URI: http://hdl.handle.net/10668/1316
metadata.dc.relation.publisherversion: http://jcem.endojournals.org/content/94/9/3234.abstract
metadata.dc.identifier.doi: 10.1210/jc.2008-2652
ISSN: 1945-7197 (Online)
0021-972X (Print)
Appears in Collections:01- Artículos - AGS Campo de Gibraltar
01- Artículos - AGS Osuna
01- Artículos - Complejo Hospitalario de Jaén
01- Artículos - Hospital Regional de Málaga

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