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Título : Low intensity vs. self-guided internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized study.
Autor : López-del-Hoyo, Yolanda
Olivan, Barbara
Luciano, Juan V
Mayoral, Fermín
Roca, Miquel
Gili, Margalida
Andres, Eva
Serrano-Blanco, Antoni
Collazo, Francisco
Araya, Ricardo
Baños, Rosa
Botella, Cristina
Magallón, Rosa
García-Campayo, Javier
Filiación: [López-del-Hoyo,Y; Olivan,B] Departamento de Psicología y Sociología, Universidad de Zaragoza, Zaragoza, Spain. [Luciano,JV; Serrano-Blanco,A] Parc Sanitari Sant Joan de Déu and Fundación Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain. [Mayoral,F] Psychiatric Service, University Hospital Carlos Haya, Malaga, Spain. [Roca,M; Gilli,M] Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca, Spain. [Andres,E] Unidad Epidemiología Clínica, Hospital 12 de Octubre, CIBER Epidemiología y Salud Pública, Madrid, Spain. [Collazo,F] Servei de Psiquiatria, Hospital Universitari Vall d'Hebron, Barcelona, Spain. [Araya,R] Academic Unit of Psychiatry, School of Social and Community Medicine, University of Bristol, Bristol, UK. [Baños,R] Universidad de Valencia, Madrid, Spain. [Botella,C; Magallón,R] Universitat Jaume I, Castellon, Spain. [Baños,R; Botella,C; García-Campayo,J] Ciber Fisiopatología de la Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, Spain.
Palabras clave : Depression
Computer-delivered psychotherapy
Randomized controlled trial
Trastorno depresivo mayor
Diseño de la investigación
Tratamiento asistido por ordenador
Resultado del tratamiento
Protocolos clínicos
Terapia cognitiva
Análisis Costo-Beneficio
MeSH: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols
Medical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychotherapy::Behavior Therapy::Cognitive Therapy
Medical Subject Headings::Health Care::Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost-Benefit Analysis
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder::Depressive Disorder, Major
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Computer Systems::Computer Communication Networks::Internet
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Design
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Therapy, Computer-Assisted
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Fecha de publicación : 11-Jan-2013
Editorial : BioMed Central
Cita Bibliográfica: López-del-Hoyo Y, Olivan B, Luciano JV, Mayoral F, Roca M, Gili M, et al. Low intensity vs. self-guided internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized study. BMC Psychiatry. 2013; 13:21
Abstract: BACKGROUND Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. METHODS The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/moderate depression recruited in primary care. They should have internet availability at home, not receive any previous psychological treatment, and not suffer from any other severe somatic or psychological disorder. They will be allocated to one of 3 treatments: a) Low intensity Internet-delivered psychotherapy + improved treatment as usual (ITAU) by GP, b) Self-guided Internet-delivered psychotherapy + ITAU or c) ITAU. Patients will be diagnosed with MINI psychiatric interview. Main outcome variable will be Beck Depression Inventory. It will be also administered EuroQol 5D (quality of life) and Client Service Receipt Inventory (consume of health and social services). Patients will be assessed at baseline, 3 and 12 months. An intention to treat and a per protocol analysis will be performed. DISCUSSION The comparisons between low intensity and self-guided are infrequent, and also a comparative economic evaluation between them and compared with usual treatment in primary. The strength of the study is that it is a multicenter, randomized, controlled trial of low intensity and self-guided Internet-delivered psychotherapy for depression in primary care, being the treatment completely integrated in primary care setting. TRIAL REGISTRATION Clinical Trials NCT01611818.
Descripción : Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Trial registration: Clinical Trials NCT01611818
Versión del editor :
DOI: 10.1186/1471-244X-13-21
ISSN : 1471-244X (Online)
Appears in Collections:01- Artículos - Hospital Regional de Málaga

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