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dc.contributor.authorLópez-del-Hoyo, Yolanda-
dc.contributor.authorOlivan, Barbara-
dc.contributor.authorLuciano, Juan V-
dc.contributor.authorMayoral, Fermín-
dc.contributor.authorRoca, Miquel-
dc.contributor.authorGili, Margalida-
dc.contributor.authorAndres, Eva-
dc.contributor.authorSerrano-Blanco, Antoni-
dc.contributor.authorCollazo, Francisco-
dc.contributor.authorAraya, Ricardo-
dc.contributor.authorBaños, Rosa-
dc.contributor.authorBotella, Cristina-
dc.contributor.authorMagallón, Rosa-
dc.contributor.authorGarcía-Campayo, Javier-
dc.identifier.citationLópez-del-Hoyo Y, Olivan B, Luciano JV, Mayoral F, Roca M, Gili M, et al. Low intensity vs. self-guided internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized study. BMC Psychiatry. 2013; 13:21es
dc.identifier.issn1471-244X (Online)-
dc.descriptionComparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Trial registration: Clinical Trials NCT01611818es
dc.description.abstractBACKGROUND Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. METHODS The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/moderate depression recruited in primary care. They should have internet availability at home, not receive any previous psychological treatment, and not suffer from any other severe somatic or psychological disorder. They will be allocated to one of 3 treatments: a) Low intensity Internet-delivered psychotherapy + improved treatment as usual (ITAU) by GP, b) Self-guided Internet-delivered psychotherapy + ITAU or c) ITAU. Patients will be diagnosed with MINI psychiatric interview. Main outcome variable will be Beck Depression Inventory. It will be also administered EuroQol 5D (quality of life) and Client Service Receipt Inventory (consume of health and social services). Patients will be assessed at baseline, 3 and 12 months. An intention to treat and a per protocol analysis will be performed. DISCUSSION The comparisons between low intensity and self-guided are infrequent, and also a comparative economic evaluation between them and compared with usual treatment in primary. The strength of the study is that it is a multicenter, randomized, controlled trial of low intensity and self-guided Internet-delivered psychotherapy for depression in primary care, being the treatment completely integrated in primary care setting. TRIAL REGISTRATION Clinical Trials
dc.description.sponsorshipThe study will be funded by the Carlos III Health Institute of the Spanish Ministry of Health and Consumption (ETES nº PI10/01083). "Red de Investigación en Actividades de Prevención y Promoción de la Salud" ((Research Network on Preventative Activities and Health Promotion) (REDIAPP-G06-170; Carlos III Health Institute of the Spanish Ministry of Health and Consumption (Red RD06/0018/0017) and Ministerio de Ciencia e Innovación (PSI2010-17563).es
dc.publisherBioMed Centrales
dc.relation.ispartofBMC psychiatryes
dc.subjectComputer-delivered psychotherapyes
dc.subjectRandomized controlled triales
dc.subjectTrastorno depresivo mayores
dc.subjectDiseño de la investigaciónes
dc.subjectTratamiento asistido por ordenadores
dc.subjectResultado del tratamientoes
dc.subjectProtocolos clínicoses
dc.subjectTerapia cognitivaes
dc.subjectAnálisis Costo-Beneficioes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocolses
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychotherapy::Behavior Therapy::Cognitive Therapyes
dc.subject.meshMedical Subject Headings::Health Care::Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost-Benefit Analysises
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder::Depressive Disorder, Majores
dc.subject.meshMedical Subject Headings::Check Tags::Femalees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Information Science::Information Science::Computing Methodologies::Computer Systems::Computer Communication Networks::Internetes
dc.subject.meshMedical Subject Headings::Check Tags::Malees
dc.subject.meshMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Agedes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Designes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Therapy, Computer-Assistedes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcomees
dc.subject.meshMedical Subject Headings::Named Groups::Persons::Age Groups::Adultes
dc.titleLow intensity vs. self-guided internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized
dc.rights.accessRightsAcceso abiertoes
dc.contributor.authoraffiliation[López-del-Hoyo,Y; Olivan,B] Departamento de Psicología y Sociología, Universidad de Zaragoza, Zaragoza, Spain. [Luciano,JV; Serrano-Blanco,A] Parc Sanitari Sant Joan de Déu and Fundación Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain. [Mayoral,F] Psychiatric Service, University Hospital Carlos Haya, Malaga, Spain. [Roca,M; Gilli,M] Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca, Spain. [Andres,E] Unidad Epidemiología Clínica, Hospital 12 de Octubre, CIBER Epidemiología y Salud Pública, Madrid, Spain. [Collazo,F] Servei de Psiquiatria, Hospital Universitari Vall d'Hebron, Barcelona, Spain. [Araya,R] Academic Unit of Psychiatry, School of Social and Community Medicine, University of Bristol, Bristol, UK. [Baños,R] Universidad de Valencia, Madrid, Spain. [Botella,C; Magallón,R] Universitat Jaume I, Castellon, Spain. [Baños,R; Botella,C; García-Campayo,J] Ciber Fisiopatología de la Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid,
Appears in Collections:01- Artículos - Hospital Regional de Málaga

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