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Title: Bovine tuberculosis in Doñana Biosphere Reserve: the role of wild ungulates as disease reservoirs in the last Iberian lynx strongholds.
Authors: Gortázar, Christian
Torres, María José
Vicente, Joaquín
Acevedo, Pelayo
Reglero, Manuel
De la Fuente, José
Negro, Juan José
Aznar-Martín, Javier
metadata.dc.contributor.authoraffiliation: [Gortázar,C; Vicente,J; Acevedo,P; Reglero,M; De la Fuente,J] IREC National Wildlife Research Institute (CSIC-UCLM-JCCM), Ciudad Real, Spain. [Torres,MJ] Departamento de Microbiología, Universidad de Sevilla, Sevilla, Spain. [De la Fuente,J] Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma, United States of America. [Negro,JJ] Department of Evolutionary Ecology, Estación Biológica Doñana, CSIC, Sevilla, Spain. [Aznar-Martín,J] Servicio de Microbiología, HH UU Virgen del Rocío, Sevilla, Spain.
Keywords: Animales Salvajes;Bovinos;Animales;Conservación de los Recursos Naturales;Ciervos;Reservorios de Enfermedades;Geografía;Modelos Biológicos;Factores de Riesgo;España;Especificidad de la Especie;Andalucia
metadata.dc.subject.mesh: Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Wild
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Cattle
Medical Subject Headings::Technology, Industry, Agriculture::Technology, Industry, and Agriculture::Conservation of Natural Resources
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Deer
Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Disease Reservoirs
Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Earth Sciences::Geography
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological
Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria::Actinomycetales::Mycobacteriaceae::Mycobacterium::Mycobacterium bovis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
Medical Subject Headings::Phenomena and Processes::Biological Phenomena::Species Specificity
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Actinomycetales Infections::Mycobacterium Infections::Tuberculosis::Tuberculosis, Bovine
Medical Subject Headings::Organisms::Eukaryota::Animals
Issue Date: 23-Jul-2008
Publisher: Public Library of Science
Citation: Gortázar C, Torres MJ, Vicente J, Acevedo P, Reglero M, de la Fuente J, et al. Bovine tuberculosis in Doñana Biosphere Reserve: the role of wild ungulates as disease reservoirs in the last Iberian lynx strongholds. PLoS ONE. 2008; 3(7):e2776
Abstract: Doñana National Park (DNP) in southern Spain is a UNESCO Biosphere Reserve where commercial hunting and wildlife artificial feeding do not take place and traditional cattle husbandry still exists. Herein, we hypothesized that Mycobacterium bovis infection prevalence in wild ungulates will depend on host ecology and that variation in prevalence will reflect variation in the interaction between hosts and environmental risk factors. Cattle bTB reactor rates increased in DNP despite compulsory testing and culling of infected animals. In this study, 124 European wild boar, 95 red deer, and 97 fallow deer were sampled from April 2006 to April 2007 and analyzed for M. bovis infection. Modelling and GIS were used to identify risk factors and intra and inter-species relationships. Infection with M. bovis was confirmed in 65 (52.4%) wild boar, 26 (27.4%) red deer and 18 (18.5%) fallow deer. In the absence of cattle, wild boar M. bovis prevalence reached 92.3% in the northern third of DNP. Wild boar showed more than twice prevalence than that in deer (p<0.001). Modelling revealed that M. bovis prevalence decreased from North to South in wild boar (p<0.001) and red deer (p<0.01), whereas no spatial pattern was evidenced for fallow deer. Infection risk in wild boar was dependent on wild boar M. bovis prevalence in the buffer area containing interacting individuals (p<0.01). The prevalence recorded in this study is among the highest reported in wildlife. Remarkably, this high prevalence occurs in the absence of wildlife artificial feeding, suggesting that a feeding ban alone would have a limited effect on wildlife M. bovis prevalence. In DNP, M. bovis transmission may occur predominantly at the intra-species level due to ecological, behavioural and epidemiological factors. The results of this study allow inferring conclusions on epidemiological bTB risk factors in Mediterranean habitats that are not managed for hunting purposes. Our results support the need to consider wildlife species for the control of bTB in cattle and strongly suggest that bTB may affect animal welfare and conservation.
Description: Journal Article; Research Support, Non-U.S. Gov't;
metadata.dc.identifier.doi: 10.1371/journal.pone.0002776
ISSN: 1932-6203 (Online)
Appears in Collections:01- Artículos - Hospital Virgen del Rocío

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