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Title: Skin lesions in children during the first wave of the SARS-CoV-2 pandemic.
Other Titles: Lesiones cutáneas en niños durante la primera ola de la pandemia por SARS-CoV-2.
Authors: Carazo Gallego, Begoña
Martín Pedraz, Laura
Galindo Zavala, Rocío
Rivera Cuello, Mercedes
Mediavilla Gradolph, Concepción
Núñez Cuadros, Esmeralda
Keywords: COVID-19;Chilblains;Exantema;Exanthema;Manifestaciones cutáneas;Perniosis;SARS-CoV-2;Skin manifestations
metadata.dc.subject.mesh: COVID-19
Cross-Sectional Studies
Skin Diseases
Issue Date: 4-May-2021
Abstract: Cutaneous manifestations have been included in COVID-19 patients' clinical spectrum. Our objective was to determine the association between skin lesions in children and SARS-CoV-2 infection, analyzing others possible infectious/autoimmune etiologies. Observational, multicenter, cross-sectional study, about children with skin manifestations from April to May 2020. The diagnosis of SARS-CoV-2 was performed by PCR in nasopharyngeal exudate and/or presence of antibodies by serology. Sixty-two children were included, 9 (14.5%) presented positive antibodies to SARS-CoV-2, with no positive PCR to SARS-Cov-2 in those patients in whom it was made. Patients with positive serology to SARS-CoV-2 presented chilblains and/or vesicular-bullous skin lesions more frequently (66.7% vs. 24.5%, p=0.019). Generalized, urticarial and maculopapular rash was more common in patients with negative antibodies (37.7 vs. 0%, p=0.047), others pathogens were isolated in 41.5% of these patients. There were no significant differences in the positivity for autoantibodies between both groups. In our study, the presence of chilblains-like and/or vesicular lesions were significantly related to SARS-CoV-2 previous contact.
metadata.dc.identifier.doi: 10.1016/j.medcli.2021.03.004
Appears in Collections:Producción 2020

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