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Title: Synthetic biology approaches to actinomycete strain improvement.
Authors: Breitling, Rainer
Avbelj, Martina
Bilyk, Oksana
Carratore, Francesco Del
Filisetti, Alessandro
Hanko, Erik K R
Iorio, Marianna
Redondo, Rosario Pérez
Reyes, Fernando
Rudden, Michelle
Severi, Emmanuele
Slemc, Lucija
Schmidt, Kamila
Whittall, Dominic R
Donadio, Stefano
García, Antonio Rodríguez
Genilloud, Olga
Kosec, Gregor
De Lucrezia, Davide
Petković, Hrvoje
Thomas, Gavin
Takano, Eriko
Keywords: actinobacteria;actinomycete;biosynthesis;biotechnology;synthetic biology
metadata.dc.subject.mesh: Actinobacteria
Industrial Microbiology
Metabolic Engineering
Synthetic Biology
Issue Date: 2021
Abstract: Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains.
metadata.dc.identifier.doi: 10.1093/femsle/fnab060
Appears in Collections:Producción 2020

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