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Title: | Synthetic biology approaches to actinomycete strain improvement. |
Authors: | Breitling, Rainer Avbelj, Martina Bilyk, Oksana Carratore, Francesco Del Filisetti, Alessandro Hanko, Erik K R Iorio, Marianna Redondo, Rosario Pérez Reyes, Fernando Rudden, Michelle Severi, Emmanuele Slemc, Lucija Schmidt, Kamila Whittall, Dominic R Donadio, Stefano García, Antonio Rodríguez Genilloud, Olga Kosec, Gregor De Lucrezia, Davide Petković, Hrvoje Thomas, Gavin Takano, Eriko |
Keywords: | actinobacteria;actinomycete;biosynthesis;biotechnology;synthetic biology |
metadata.dc.subject.mesh: | Actinobacteria Industrial Microbiology Metabolic Engineering Synthetic Biology |
Issue Date: | 2021 |
Abstract: | Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains. |
URI: | http://hdl.handle.net/10668/17855 |
metadata.dc.identifier.doi: | 10.1093/femsle/fnab060 |
Appears in Collections: | Producción 2020 |
Files in This Item:
File | Size | Format | |
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PMC8195692.pdf | 217,34 kB | Adobe PDF | View/Open |
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