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Title: Bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient
Authors: Bernabeu-Wittel, J
Luque, R
Corbi, R
Mantrana-Bermejo, M
Navarrete, M
Vallejo, A
Bernabeu-Wittel, M
metadata.dc.contributor.authoraffiliation: [Bernabeu-Wittel,J; Corbi,R; Mantrana-Bermejo,M] Department of Dermatology, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain. [Luque,R; Bernabeu-Wittel,M] Department of Infectious Diseases, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain. [Navarrete,M] Department of Pathology, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain. [Vallejo,A] Department of AIDS and Viral Hepatitis Study Group, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain.
Keywords: Bartonella quintana;Bartonella henselae;Immunocompetent;Infecciones por Bartonella;Proliferación de la Célula;Diagnóstico Diferencial;Doxiciclina;Endotelio Vascular;Huésped Inmunocomprometido;Angiomatosis Bacilar
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Bartonellaceae Infections
Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnosis, Differential
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Tetracyclines::Doxycycline
Medical Subject Headings::Anatomy::Tissues::Epithelium::Endothelium::Endothelium, Vascular
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunocompromised Host
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Skin Diseases, Bacterial::Angiomatosis, Bacillary
Issue Date: 2010
Publisher: Medknow Publications
Citation: Bernabeu-Wittel J, Luque R, Corbi R, Mantrana-Bermejo M, Navarrete M, Vallejo A, et al. Bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient. Indian J Dermatol Venereol Leprol. 2010; 76(6):682-5
Abstract: Bacillary angiomatosis is a recently described infectious disease that usually affects immunosupressed hosts with a previous history of contact with cats. We report a rare case of bacillary angiomatosis in an immunocompetent 59-year-old woman with no history of previous exposure to cats, and atypical clinical features (fever and subcutaneous nodules with ulceration on the left ankle). Histopathology of the lesion showed extensive ulceration and reactive tumor-like vascular proliferation of the blood vessels with swollen endothelial cells and an inflammatory infiltrate including neutrophils and lymphocytes in the dermis and subcutis. Staining with the Warthin-Starry method demonstrated the presence of clustered bacilli located in the extracellular matrix adjacent to the proliferating endothelial cells. Diagnosis was confirmed with the detection of Bartonella spp. DNA in the affected skin and in bone marrow using polymerase chain reaction.
Description: Case Reports; Journal Article;
metadata.dc.identifier.doi: 10.4103/0378-6323.72469
ISSN: 0973-3922 (Online)
0378-6323 (Print)
Appears in Collections:01- Artículos - Hospital Virgen del Rocío

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