Please use this identifier to cite or link to this item:
Title: Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament.
Authors: Fernández-Aranda, Fernando
Sauchelli, Sarah
Pastor, Antoni
González, Marcela L
Torre, Rafael de la
Granero, Roser
Jiménez-Murcia, Susana
Baños, Rosa
Botella, Cristina
Fernández-Real, José M
Fernández-García, José C
Frühbeck, Gema
Gómez-Ambrosi, Javier
Rodríguez, Roser
Tinahones, Francisco J
Arcelus, Jon
Fagundo, Ana B
Agüera, Zaida
Miró, Jordi
Casanueva, Felipe F
metadata.dc.contributor.authoraffiliation: [Fernández-Aranda,F; Sauchelli,S; Jiménez-Murcia,S; Fagundo,AB; Agüera,Z] Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain. [Fernández-Aranda,F; Pastor,A; Torre,R de la; Granero,R; Jiménez-Murcia,S; Baños,R; Botella,C; Fernández-Real,JM; Fernández-García,JC; Frühbeck,G; Gómez-Ambrosi,J; Rodríguez,R; Tinahones,FJ; Fagundo,AB; Agüera,Z; Casanueva,FF] CIBER Fisiopatología Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, Spain. [Fernández-Aranda,F; Jiménez-Murcia,S] Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain [Pastor,A] Department of Pharmacology, School of Medicine, Universitat Autónoma de Barcelona, Spain. [Pastor,A; Torre,R de la] Human Pharmacology and Clinical Neurosciences Research Group, Neuroscience Research Program, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. [González,M] Department of Psychology, Universitat Rovira i Virgili, Tarragona, Spain. [Torre,R de la; Miró,J] Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain. [Granero,R] Departament de Psicobiologia i Metodologia, Universitat Autònoma de Barcelona, Spain. [Baños,R] Department of Psychological, Personality, Evaluation and Treatment of the University of Valencia, Spain. [Botella,C] Department of Basic Psychology, Clinic and Psychobiology of the University Jaume I, Castelló, Spain. [Fernández-Real,JM; Rodríguez,R] Department of Diabetes, Endocrinology and Nutrition, Institut d’Investigació Biomèdica de Girona (IdlBGi) Hospital Dr Josep Trueta, Girona, Spain. [Fernández-García,JC; Tinahones,FJ] Department of Diabetes, Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain. [Frühbeck,G; Gómez-Ambrosi,J] Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, Pamplona, Spain. [Arcelus,J] Eating Disorders Service, Glenfield University Hospital, Leicester, United Kingdom. [Casanueva,FF] Department of Medicine, Endocrinology Division, Santiago de Compostela University, Complejo Hospitalario Universitario, Santiago de Compostela, Spain.
Keywords: Esfuerzo físico;Endocannabinoides;Ácidos araquidónicos;Índice de masa corporal;Temperamento;Mujer;Obesidad
metadata.dc.subject.mesh: Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Physical Exertion
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids
Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Arachidonic Acids
Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Personality::Temperament
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity
Issue Date: 7-Aug-2014
Publisher: Public Library of Science
Citation: Fernández-Aranda F, Sauchelli S, Pastor A, González ML, Torre R de la, Granero R, et al. Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament. PLoS ONE. 2014; 9(8):e104534
Abstract: BACKGROUND Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional study were to 1) examine differences among distinct BMI groups on daytime physical activity and time spent in moderate-vigorous physical activity (MVPA), temperament traits and plasma endocannabinoid concentrations; and 2) explore the association and interaction between MVPA, temperament, endocannabinoids and BMI. METHODS Physical activity was measured with the wrist-worn accelerometer Actiwatch AW7, in a sample of 189 female participants (43 morbid obese, 30 obese, and 116 healthy-weight controls). The Temperament and Character Inventory-Revised questionnaire was used to assess personality traits. BMI was calculated by bioelectrical impedance analysis via the TANITA digital scale. Blood analyses were conducted to measure levels of endocannabinoids and endocannabinoid-related compounds. Path-analysis was performed to examine the association between predictive variables and MVPA. RESULTS Obese groups showed lower MVPA and dysfunctional temperament traits compared to healthy-weight controls. Plasma concentrations of 2-arachidonoylglyceryl (2-AG) were greater in obese groups. Path-analysis identified a direct effect between greater MVPA and low BMI (b = -0.13, p = .039) and high MVPA levels were associated with elevated anandamide (AEA) levels (b = 0.16, p = .049) and N-oleylethanolamide (OEA) levels (b = 0.22, p = .004), as well as high Novelty seeking (b = 0.18, p<.001) and low Harm avoidance (b = -0.16, p<.001). CONCLUSIONS Obese individuals showed a distinct temperament profile and circulating endocannabinoids compared to controls. Temperament and endocannabinoids may act as moderators of the low MVPA in obesity.
Description: Journal Article;
metadata.dc.identifier.doi: 10.1371/journal.pone.0104534
ISSN: 1932-6203 (Online)
Appears in Collections:01- Artículos - Hospital Virgen de la Victoria

Files in This Item:
File Description SizeFormat 
Fernandez-Aranda_Moderate.pdfArtículo publicado344,05 kBAdobe PDFView/Open

This item is protected by original copyright

This item is licensed under a Creative Commons License Creative Commons