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Title: Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study.
Authors: Orgaz-Molina, Jacinto
Magro-Checa, César
Arrabal-Polo, Miguel A
Raya-Álvarez, Enrique
Naranjo, Ramón
Buendía-Eisman, Agustín
Arias-Santiago, Salvador
metadata.dc.contributor.authoraffiliation: [Orgaz-Molina,J; Ramón Naranjo,E; Buendía-Eisman,A; Arias-Santiago,S] Dermatology Department San Cecilio; University Hospital; Granada, Spain. [Magro-Checa,C; Raya-Álvarez,E] Rheumatology Department, San Cecilio; University Hospital [Arrabal-Polo,M A; Raya-Álvarez,E; Buendía-Eisman, A; Arias-Santiago, S;] School of Medicine, University of Granada, Spain. [Arias-Santiago,S] Baza General Hospital, Granada, Spain
Keywords: Psoriasis;Vitamin D;Metabolic syndrome;Cardiovascular risk;Psoriasis;Vitamina D;Enfermedades metabólicas;Enfermedades cardiovasculares
metadata.dc.subject.mesh: Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Statistical::Logistic Models
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases, Papulosquamous::Psoriasis
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::Light::Sunlight
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Vitamin D-Binding Protein
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition::Deficiency Diseases::Avitaminosis::Vitamin D Deficiency
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Vital Signs::Blood Pressure
Issue Date: Mar-2014
Publisher: Society for Publication of Acta Dermato-Venereologica
Citation: Orgaz-Molina J, Magro-Checa C, Arrabal-Polo MA, Raya-Álvarez E, Naranjo R, Buendía-Eisman A, et al. Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study. Acta Derm. Venereol.. 2014; 94(2):142-5
Abstract: Vitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program-Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 control subjects, matched by sex and age. The patients with psoriasis showed significantly lower level of 25-OHD than controls (30.5 vs. 38.3 ng/ml; p = 0.0001). Patients with MeS had significantly lower serum levels of 25-OHD than those without MeS (24.1 ± 7.5 vs. 32.8 ± 8.9, p = 0.007), and a negative correlation was found between 25-OHD and waist circumference, diastolic blood pressure, fasting glucose, and triglyceridaemia. In the control group no significant correlation between 25-OHD and MeS was found. Al-though the sample was small, our results suggest a potential protective role for 25-OHD in the metabolic profile of patients with psoriasis without arthritis.
Description: Journal Article;
metadata.dc.identifier.doi: 10.2340/00015555-1642
ISSN: 1651-2057 (Online)
0001-5555 (Print)
Appears in Collections:01- Artículos - Hospital San Cecilio

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