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Título : Plasmapheresis as treatment for hyperlipidemic pancreatitis.
Autor : Ramírez-Bueno, A
Salazar-Ramírez, C
Cota-Delgado, F
Torre-Prados, M V de la
Valdivielso, P
Filiación: [Ramírez-Bueno,A; Valdivielso,P] Unidad de Gestión Clínica de Medicina Interna, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Salazar-Ramírez,C; Cota-Delgado,F; Torre-Prados,M V de la] Unidad de Gestión Clínica de Cuidados Críticos y Urgencias, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Valdivielso,P] Unidad de Gestión Clínica de Cuidados Críticos y Urgencias, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Spain.
Palabras clave : Plasmapheresis;Acute pancreatitis;Hypertriglyceridemic pancreatitis;Severe hypertriglyceridemia;Plasmaféresis;Pancreatitis;Hiperlipidemias;Enfermedad aguda;Índice de severidad de la enfermedad;Resultado del tratamiento
MeSH: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Blood Component Removal::Plasmapheresis
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::Dyslipidemias::Hyperlipidemias
Medical Subject Headings::Diseases::Digestive System Diseases::Pancreatic Diseases::Pancreatitis
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Acute Disease
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Severity of Illness Index
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Fecha de publicación : feb-2014
Editorial : Elsevier
Cita Bibliográfica: Ramírez-Bueno A, Salazar-Ramírez C, Cota-Delgado F, Torre-Prados MV de la, Valdivielso P. Plasmapheresis as treatment for hyperlipidemic pancreatitis. Eur. J. Intern. Med.. 2014 ; 25(2):160-3
Abstract: BACKGROUND Severe hypertriglyceridemia with an accumulation of chylomicrons and triglyceride figures >1000 mg/dL can cause acute pancreatitis, a potentially fatal complication. The option of rapid reduction in triglyceride concentrations is attractive and possible with plasmapheresis. METHODS We present the results of an analysis of 11 patients admitted to the intensive care unit with severe hypertriglyceridemic pancreatitis and treated with plasmapheresis. The procedure was repeated until serum triglycerides were below 1000 mg/dL. We recorded anthropometric, clinical data as well as final outcome. RESULTS In eight patients a single plasma exchange was sufficient to reduce triglyceride figures <1000 mg/dL. Only three patients died, all with the worst severity indexes and who experienced the longest delay before the procedure. CONCLUSIONS Our results, together with a review of the literature, confirm the need for a randomized clinical trial to compare conventional treatment vs. plasmapheresis in patients with severe hypertriglyceridemic pancreatitis.
Descripción : Journal Article;
URI: http://hdl.handle.net/10668/1874
Versión del editor : http://www.sciencedirect.com/science/article/pii/S0953620513009102
DOI: 10.1016/j.ejim.2013.08.701
ISSN : 1879-0828 (Online)
0953-6205 (Print)
Aparece en las colecciones: 01- Artículos - Hospital Virgen de la Victoria
01- Artículos - IBIMA. Instituto de Investigación Biomédica de Málaga

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