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Title: Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up.
Authors: Pascual, Isaac
Muñoz-García, Antonio J
López-Otero, Diego
Avanzas, Pablo
Jiménez-Navarro, Manuel F
Cid-Alvarez, Belén
Valle, Raquel del
Alonso-Briales, Juan H
Ocaranza-Sánchez, Raimundo
Hernández, José M
Trillo-Nouche, Ramiro
Morís, César
metadata.dc.contributor.authoraffiliation: [Pascual,I; Avanzas,P; Valle,R del; Morís,C] Área del Corazón, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. [Muñoz-García,AJ; Jiménez-Navarro,MF; Alonso-Briales,JH; Hernández,JM] Department of Cardiology, Hospital Universitario Vírgen de la Victoria, Málaga, Spain. [López-Otero,D; Cid-Álvarez,B; Ocaranza-Sánchez,R; Trillo-Nouche,R] Department of Cardiology, Complejo Hospitalario Universitario de Santiago de Compostela, A Coruña, Spain.
Keywords: Aortic stenosis;High surgical risk;Transcatheter aortic valve;Very elderly patients;Reemplazo de la válvula aórtica transcatéter;Humanos;Anciano;Estenosis de la válvula aórtica;Tasa de supervivencia;Hemorragia
metadata.dc.subject.mesh: Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Aortic Valve Stenosis
Medical Subject Headings::Health Care::Population Characteristics::Demography::Vital Statistics::Mortality::Survival Rate
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Hemorrhage
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Prosthesis Implantation::Heart Valve Prosthesis Implantation
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Issue Date: 4-Jul-2015
Publisher: Institute of Geriatric Cardiology, Chinese PLA General Hospital
Citation: Pascual I, Muñoz-García AJ, López-Otero D, Avanzas P, Jiménez-Navarro MF, Cid-Álvarez B, et al. Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up. J Geriatr Cardiol. 2015; 12(4):340-5
Abstract: OBJECTIVE To evaluate immediate transcatheter aortic valve implantation (TAVI) results and medium-term follow-up in very elderly patients with severe and symptomatic aortic stenosis (AS). METHODS This multicenter, observational and prospective study was carried out in three hospitals. We included consecutive very elderly (> 85 years) patients with severe AS treated by TAVI. The primary endpoint was to evaluate death rates from any cause at two years. RESULTS The study included 160 consecutive patients with a mean age of 87 ± 2.1 years (range from 85 to 94 years) and a mean logistic EuroSCORE of 18.8% ± 11.2% with 57 (35.6%) patients scoring ≥ 20%. Procedural success rate was 97.5%, with 25 (15.6%) patients experiencing acute complications with major bleeding (the most frequent). Global mortality rate during hospitalization was 8.8% (n = 14) and 30-day mortality rate was 10% (n = 16). Median follow up period was 252.24 ± 232.17 days. During the follow-up period, 28 (17.5%) patients died (17 of them due to cardiac causes). The estimated two year overall and cardiac survival rates using the Kaplan-Meier method were 71% and 86.4%, respectively. Cox proportional hazard regression showed that the variable EuroSCORE ≥ 20 was the unique variable associated with overall mortality. CONCLUSIONS TAVI is safe and effective in a selected population of very elderly patients. Our findings support the adoption of this new procedure in this complex group of patients.
Description: Journal Article;
metadata.dc.identifier.doi: 10.11909/j.issn.1671-5411.2015.04.005
ISSN: 1671-5411 (Online)
Appears in Collections:01- Artículos - Hospital Virgen de la Victoria

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