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http://hdl.handle.net/10668/2152| Title: | Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study. |
| Authors: | Moreno-Ramírez, David Ojeda-Vila, Teresa Ríos-Martín, Juan J Nieto-García, Adoración Ferrándiz, Lara |
| metadata.dc.contributor.authoraffiliation: | [Moreno-Ramírez,D; Ojeda-Vila,T; Ferrándiz,L] Dermatology Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain. [Ríos-Martín,JJ] Pathology Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain. [Nieto-García,A] Public Health and Epidemiology Department, Medical School, Universidad de Sevilla, Seville, Spain. |
| Keywords: | Malignant melanoma;Prognostic predictors;Thin melanoma;Early-stage malignant melanoma;Age;Sex;Estudios transversales;Modelos logísticos;Melanoma |
| metadata.dc.subject.mesh: | Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Analysis of Variance Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies Medical Subject Headings::Check Tags::Female Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Logistic Models Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neuroendocrine Tumors::Melanoma Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds Ratio |
| Issue Date: | 4-Nov-2015 |
| Publisher: | Society for the Publication of Acta Dermato-Venereologica |
| Citation: | Moreno-Ramírez D, Ojeda-Vila T, Ríos-Martín JJ, Nieto-García A, Ferrándiz L. Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study. Acta Derm. Venereol. 2015; 95(8):940-2 |
| Abstract: | Age and sex have been identified as predictors of outcome in malignant melanoma (MM). This aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2430 patients with MM were recruited. Cases of in situ-T1 MM were more frequent than T2-T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0-29 years (1.18), and 30-59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis-T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM. |
| Description: | Journal Article; |
| URI: | http://hdl.handle.net/10668/2152 |
| metadata.dc.relation.publisherversion: | http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-2115 |
| metadata.dc.identifier.doi: | 10.2340/00015555-2115 |
| ISSN: | 1651-2057 (Online) 0001-5555 (Print) |
| Appears in Collections: | 01- Artículos - Hospital Virgen Macarena |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Moreno_RoleAgeSex.pdf | Artículo publicado | 302,36 kB | Adobe PDF | View/Open |
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