Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/2231
Título : Prognostic value of a high level of circulating endothelial cells in patients with HER2-recurrent or metastatic breast cancer treated with bevacizumab in combination with paclitaxel and gemcitabine as fi rst-line therapy
Autor : Manso, L
Ciruelos, E
Codes, M
De la Haba, J
Galan, A
Baena, J
Jaen, A
Gil, M
Murias, A
Blancas, I
Gonzalez, E
Perez, D
Bayo, JL
Mel, J
Garcia-Martinez, E
Cubedo, R
Salvador, J
Filiación: [Manso,L; Ciruelos,E] Hospital 12 de Octubre, Madrid, Spain. [Codes,M] Hospital Virgen Macarena, Sevilla, Spain. [De la Haba,J] Hospital Reina Sofía, Córdoba, Spain. [Galan,A] Hospital de Sagunto, Spain. [Baena,J] Hospital Puerta del Mar, Cádiz, Spain. [Jaen,A] Hospital de Jaen, Spain. [Gil,M] ICO, Bellvitge, Spain. [Murias,A] Hospital Insular, Las Palmas de Gran Canaria, Spain. [Blanca,I] Hospital San Cecilio, Granada, Spain. [Gonzalez,E] Hospital Virgen de las Nieves, Granada, Spain. [Perez,D] Hospital Costa del Sol, Marbella, Spain; [Bayo,JL] Hospital Juan Ramón Jimenez, Huelva, Spain. [Mel,J] Hospital Xeral-Calde, Lugo, Spain. [Garcia-Martinez,E] Hospital Morales Messeguer, Murcia, Spain. [Cubedo,R] Hospital Puerta de Hierro, Madrid, Spain. [Salvador,J] Hospital Universitario de Valme, Sevilla, Spain.
Palabras clave : Neoplasias
Bevacizumab
Anticuerpos monoclonales humanizados
Desoxicitidina
Progresión de la enfermedad
Células endoteliales
Paclitaxel
MeSH: Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal::Antibodies, Monoclonal, Humanized
Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidine Nucleosides::Cytidine::Deoxycytidine
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival
Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Diseases::Neoplasms
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Alicyclic::Cycloparaffins::Cyclodecanes::Taxoids::Paclitaxel
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation, Computer-Assisted::Tomography, X-Ray Computed
Fecha de publicación : 16-Nov-2011
Editorial : BioMed Central
Cita Bibliográfica: Manso L, Ciruelos E, Codes M, De la Haba J, Galan A, Baena J, et al. Prognostic value of a high level of circulating endothelial cells in patients with HER2-recurrent or metastatic breast cancer treated with bevacizumab in combination with paclitaxel and gemcitabine as fi rst-line therapy. Breast Cancer Res. 2011; 13(Suppl 2): P4.
Abstract: Circulating endothelial cells (CECs) are shed from vessels and enter the circulation reflecting endothelial damage. Increased numbers of CECs have been documented in cancer, and appear to correlate with progression of the tumor. Bevacizumab (B) in combination with CT improves progression-free survival (PFS) of first-line treatments and may modify tumor cell intravasation and CEC/CTC levels.
URI: http://hdl.handle.net/10668/2231
Versión del editor : http://breast-cancer-research.biomedcentral.com/articles/supplements/volume-13-supplement-2
DOI: 10.1186/bcr3025
ISSN : 1465-542X (Online)
1465-5411 (Print)
Appears in Collections:01- Artículos - Hospital de Valme
01- Artículos - Hospital Juan Ramón Jiménez
01- Artículos - APES Costa del Sol
01- Artículos - Hospital Virgen de las Nieves
01- Artículos - Hospital San Cecilio
01- Artículos - Complejo Hospitalario de Jaén
01- Artículos - Hospital Puerta del Mar
01- Artículos - Hospital Reina Sofía
01- Artículos - Hospital Virgen Macarena

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