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Title: Localized mucosal leishmaniasis caused by Leishmania infantum mimicking cancer in the rhinolaryngeal region.
Authors: Cobo, Fernando
Rodríguez-Granger, Javier
Gómez-Camarasa, Cristina
Sampedro, Antonio
Aliaga-Martínez, Luis
Navarro, José María
Fernández, José Gutiérrez
metadata.dc.contributor.authoraffiliation: [Cobo,F; Rodríguez-Granger,J; Gómez-Camarasa,C; Sampedro,N; Navarro,JM] Microbiology Department, Hospital Virgen de las Nieves,Granada, Spain. [Aliaga-Martínez,L] Internal Medicine Department, Hospital Virgen de las Nieves, Granada, Spain. [Gutiérrez Fernández,J] Microbiology Department, School of Medicine, University of Granada, Granada, Spain
Keywords: Leishmania infantum;Mucosal leishmaniasis;Giemsa;Culture;Cancer;Leishmaniasis mucocutánea;Reacción en cadena de la polimerasa;Parásitos;Anfotericina B;Meglumina
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Parasitic Diseases::Protozoan Infections::Euglenozoa Infections::Leishmaniasis::Leishmaniasis, Cutaneous::Leishmaniasis, Mucocutaneous
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction
Medical Subject Headings::Organisms::Eukaryota::Animals::Invertebrates::Parasites
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Lactones::Macrolides::Amphotericin B
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Sugar Alcohols::Sorbitol::Meglumine
Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Laryngeal Diseases::Voice Disorders::Hoarseness
Issue Date: Sep-2016
Publisher: Elsevier
Citation: Cobo F, Rodríguez-Granger J, Gómez-Camarasa C, Sampedro A, Aliaga-Martínez L, Navarro JM, et al. Localized mucosal leishmaniasis caused by Leishmania infantum mimicking cancer in the rhinolaryngeal region. Int J Infect Dis.. 2016; 50:54-
Abstract: The clinical, microbiological, and histopathological findings of six patients with mucosal leishmaniasis are reported. Five of these patients were Spanish with no history of travel abroad, while the other was from Bolivia but had lived in Spain for more than 5 years. Two patients had no underlying disease, while the other four had several other medical conditions. Lesions were located in the nose in three patients and in the larynx in the other three. Symptoms included difficulty in swallowing, nasal obstruction, dysphonia, and polypoid lesions mimicking cancer. The diagnosis was based on the identification of parasites, or on PCR assay or culture. Five patients were treated with liposomal amphotericin B and the other with antimonial compounds.
Description: Journal Article;
metadata.dc.identifier.doi: 10.1016/j.ijid.2016.08.003
ISSN: 1878-3511 (Online)
1201-9712 (Print)
Appears in Collections:01- Artículos - Complejo Hospitalario Universitario de Granada

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