Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/261
Title: A comparative study of dyslipidaemia in men and woman with androgenic alopecia
Authors: Arias-Santiago, Salvador
Gutierrez-Salmeron, Maria Teresa
Buendia-Eisman, Agustin
Giron-Prieto, Maria Sierra
Naranjo-Sintes, Ramon
metadata.dc.contributor.authoraffiliation: [Arias-Santiago S; Gutierrez-Salmeron MT; Buendia-Eisman A; Giron-Prieto MS; Naranjo-Sintes R] Departamento de Dermatología, Hospital Universitario San Cecilio, Granada, Spain
Keywords: Edad de Inicio;Alopecia;Estudios de Casos y Controles;Distribución de Chi-Cuadrado;Colesterol LDL;Dislipidemias;Medición de Riesgo;Factores de Riesgo;Marcadores Biológicos;Índice de Masa Corporal;Colesterol HDL;Colesterol;Oportunidad Relativa;Colesterol, LDL;Distribución por Sexo;Prevalencia;Humanos;Femenino;Masculino;España
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Statistical Distributions::Chi-Square Distribution
Medical Subject Headings::Chemicals and Drugs::Lipids::Sterols::Cholesterol
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDL
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, LDL::Cholesterol, LDL
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::Dyslipidemias
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds Ratio
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Assessment
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Demography::Sex Distribution
Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Female
Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Male
Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
Issue Date: Sep-2010
Publisher: Society for the Publication of Acta Dermato-Venereologica
Citation: Arias-Santiago S, Sanchez-Cano D, Callejas-Rubio JL, Fernández-Pugnaire MA, Ortego-Centeno N. Adalimumab treatment for SAPHO syndrome. Acta Derm Venereol. 2010 May;90(3):301–2.
Abstract: Several studies have analyzed the relationship between androgenetic alopecia and cardiovascular disease (mainly heart disease). However few studies have analyzed lipid values in men and women separately. This case-control study included 300 patients consecutively admitted to an outpatient clinic, 150 with early onset androgenetic alopecia (80 males and 70 females) and 150 controls (80 males and 70 females) with other skin diseases. Female patients with androgenic alopecia showed significant higher triglycerides values (123.8 vs 89.43 mg/dl, p = 0.006), total cholesterol values (196.1 vs 182.3 mg/dl, p = 0.014), LDL-C values (114.1 vs 98.8 mg/dl, p = 0.0006) and lower HDL-C values (56.8 vs 67.7 mg/dl, p <0.0001) versus controls respectively. Men with androgenic alopecia showed significant higher triglycerides values (159.7 vs 128.7 mg/dl, p = 0.04) total cholesterol values (198.3 vs 181.4 mg/dl, p = 0.006) and LDL-C values (124.3 vs 106.2, p = 0.0013) versus non-alopecic men. A higher prevalence of dyslipidemia in women and men with androgenic alopecia has been found. The elevated lipid values in these patients may contribute, alongside other mechanisms, to the development of cardiovascular disease in patient with androgenic alopecia.
metadata.dc.description.otherabstracts: Varios estudios han analizado la relación entre la alopecia androgenética y las enfermedades cardiovasculares (especialmente las cardiopatías). Sin embargo pocos estudios han analizado los valores de lípidos en hombres y mujeres por separado. Este caso-control de estudio incluyó a 300 pacientes consecutivos ingresados ​​en una clínica para pacientes ambulatorios, 150 con la aparición temprana alopecia androgenética (80 hombres y mujeres 70) y 150 controles (80 hombres y mujeres 70) con enfermedades de la piel. Mujeres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (123,8 vs 89,43 mg / dl, p = 0,006), valores de colesterol total (196,1 vs 182,3 mg / dl, p = 0,014), los valores de LDL-C (114,1 vs 98,8 mg / dl , p = 0,0006) y más baja los valores de HDL-C (56,8 vs 67,7 mg / dl, p <0,0001) en comparación con los controles, respectivamente. Los hombres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (159,7 vs 128,7 mg / dl, p = 0,04) el colesterol total valores (198,3 vs 181,4 mg / dl, p = 0,006) y LDL-C los valores (124,3 vs 106,2, p = 0,0013) en comparación con alopecia hombres . Una mayor prevalencia de la dislipidemia en las mujeres y los hombres con alopecia androgénica se ha encontrado. Los valores elevados de lípidos en estos pacientes puede contribuir, junto con otros mecanismos, para el desarrollo de enfermedad cardiovascular en pacientes con alopecia androgénica
URI: http://hdl.handle.net/10668/261
metadata.dc.relation.publisherversion: http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-0926
metadata.dc.identifier.doi: 10.2340/00015555-0926
ISSN: 0001-5555 (Online)
Appears in Collections:01- Artículos - Hospital San Cecilio

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