Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/261
Título : A comparative study of dyslipidaemia in men and woman with androgenic alopecia
Autor : Arias-Santiago, Salvador
Gutierrez-Salmeron, Maria Teresa
Buendia-Eisman, Agustin
Giron-Prieto, Maria Sierra
Naranjo-Sintes, Ramon
Filiación: [Arias-Santiago S; Gutierrez-Salmeron MT; Buendia-Eisman A; Giron-Prieto MS; Naranjo-Sintes R] Departamento de Dermatología, Hospital Universitario San Cecilio, Granada, Spain
Palabras clave : Edad de Inicio
Alopecia
Estudios de Casos y Controles
Distribución de Chi-Cuadrado
Colesterol LDL
Dislipidemias
Medición de Riesgo
Factores de Riesgo
Marcadores Biológicos
Índice de Masa Corporal
Colesterol HDL
Colesterol
Oportunidad Relativa
Colesterol, LDL
Distribución por Sexo
Prevalencia
Humanos
Femenino
Masculino
España
MeSH: Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Statistical Distributions::Chi-Square Distribution
Medical Subject Headings::Chemicals and Drugs::Lipids::Sterols::Cholesterol
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDL
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, LDL::Cholesterol, LDL
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::Dyslipidemias
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds Ratio
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Assessment
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Demography::Sex Distribution
Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Female
Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Male
Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
Fecha de publicación : Sep-2010
Editorial : Society for the Publication of Acta Dermato-Venereologica
Cita Bibliográfica: Arias-Santiago S, Sanchez-Cano D, Callejas-Rubio JL, Fernández-Pugnaire MA, Ortego-Centeno N. Adalimumab treatment for SAPHO syndrome. Acta Derm Venereol. 2010 May;90(3):301–2.
Abstract: Several studies have analyzed the relationship between androgenetic alopecia and cardiovascular disease (mainly heart disease). However few studies have analyzed lipid values in men and women separately. This case-control study included 300 patients consecutively admitted to an outpatient clinic, 150 with early onset androgenetic alopecia (80 males and 70 females) and 150 controls (80 males and 70 females) with other skin diseases. Female patients with androgenic alopecia showed significant higher triglycerides values (123.8 vs 89.43 mg/dl, p = 0.006), total cholesterol values (196.1 vs 182.3 mg/dl, p = 0.014), LDL-C values (114.1 vs 98.8 mg/dl, p = 0.0006) and lower HDL-C values (56.8 vs 67.7 mg/dl, p <0.0001) versus controls respectively. Men with androgenic alopecia showed significant higher triglycerides values (159.7 vs 128.7 mg/dl, p = 0.04) total cholesterol values (198.3 vs 181.4 mg/dl, p = 0.006) and LDL-C values (124.3 vs 106.2, p = 0.0013) versus non-alopecic men. A higher prevalence of dyslipidemia in women and men with androgenic alopecia has been found. The elevated lipid values in these patients may contribute, alongside other mechanisms, to the development of cardiovascular disease in patient with androgenic alopecia.
Resumen: Varios estudios han analizado la relación entre la alopecia androgenética y las enfermedades cardiovasculares (especialmente las cardiopatías). Sin embargo pocos estudios han analizado los valores de lípidos en hombres y mujeres por separado. Este caso-control de estudio incluyó a 300 pacientes consecutivos ingresados ​​en una clínica para pacientes ambulatorios, 150 con la aparición temprana alopecia androgenética (80 hombres y mujeres 70) y 150 controles (80 hombres y mujeres 70) con enfermedades de la piel. Mujeres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (123,8 vs 89,43 mg / dl, p = 0,006), valores de colesterol total (196,1 vs 182,3 mg / dl, p = 0,014), los valores de LDL-C (114,1 vs 98,8 mg / dl , p = 0,0006) y más baja los valores de HDL-C (56,8 vs 67,7 mg / dl, p <0,0001) en comparación con los controles, respectivamente. Los hombres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (159,7 vs 128,7 mg / dl, p = 0,04) el colesterol total valores (198,3 vs 181,4 mg / dl, p = 0,006) y LDL-C los valores (124,3 vs 106,2, p = 0,0013) en comparación con alopecia hombres . Una mayor prevalencia de la dislipidemia en las mujeres y los hombres con alopecia androgénica se ha encontrado. Los valores elevados de lípidos en estos pacientes puede contribuir, junto con otros mecanismos, para el desarrollo de enfermedad cardiovascular en pacientes con alopecia androgénica
URI: http://hdl.handle.net/10668/261
Versión del editor : http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-0926
DOI: 10.2340/00015555-0926
ISSN : 0001-5555 (Online)
Appears in Collections:01- Artículos - Hospital San Cecilio

Files in This Item:
File Description SizeFormat 
Arias_AComparativeStudy.pdfArtículo publicado398,78 kBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons