Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/2611
Título : The study protocol for a non-randomized controlled clinical trial using a genotype-guided strategy in a dataset of patients who undergone percutaneous coronary intervention with stent
Autor : Dávila-Fajardo, Cristina Lucía
Sánchez-Ramos, Jesús
Diaz- Villamarín, Xando
Martínez-González, Luis Javier
Toledo Frías, Pablo
Martínez Huertas, Susana
Burillo Gómez, Francisco
Caballero Borrego, Juan
Bautista Pavés, Alicia
Marín Guzmán, Mª Carmen
Ramirez Hernández, José Antonio
Correa Vilches, Concepción
Cabeza Barrera, Jose
Filiación: [Dávila-Fajardo,CL; Diaz- Villamarín,X; Ramirez Hernández,JA; Cabeza Barrera,J] Department of Clinical Pharmacy, Granada University Hospital. [Sánchez-Ramos,J; Toledo Frías,P; Martínez Huertas,S; Burillo Gómez,F; Caballero Borrego,J; Bautista Pavés,A; Marín Guzmán,MC; Correa Vilches,C] Department of Cardiology, Granada University Hospital. [Dávila-Fajardo,CL; Diaz- Villamarín,X; Ramirez Hernández,JA; Cabeza Barrera,J; Sánchez-Ramos,J; Toledo Frías,P; Martínez Huertas,S; Burillo Gómez,F; Caballero Borrego,J; Bautista Pavés,A; Marín Guzmán,MC; Correa Vilches,C] Institute for Biomedical Research, ibs., Granada, Spain. [Martínez-González,LJ] Genomics Unit, Centre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, Health Sciences Technology Park, Granada, Spain.
Palabras clave : Clinical trial protocol
Protocolos clínicos
Formularios de consentimiento
Citocromos
Estudios de seguimiento
Genotipo
Hemorragia
Glicoproteínas p
Intervención coronaria percutánea
Tamaño de la muestra
Tomografía computarizada por rayos x
MeSH: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Data Collection::Records as Topic::Consent Forms
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Cytochromes
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies
Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Hemorrhage
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::ATP-Binding Cassette Transporters::P-Glycoproteins
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Vascular Surgical Procedures::Endovascular Procedures::Percutaneous Coronary Intervention
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Sample Size
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Prostheses and Implants::Stents
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Tomography::Tomography, X-Ray::Tomography, X-Ray Computed
Fecha de publicación : Feb-2017
Editorial : Elsevier
Cita Bibliográfica: Dávila-Fajardo CL, Sánchez-Ramos J, Díaz Villamarín X, Martínez-González LJ, Toledo Frías P, Martínez Huertas S et al. The study protocol for a non-randomized controlled clinical trial using a genotype-guided strategy in a dataset of patients who undergone percutaneous coronary intervention with stent. Data Brief. 2017, Feb ;10:518-524
Abstract: This article contains data related to the research article entitled "Results of genotype-guided antiplatelet therapy in patients undergone percutaneous coronary intervention with stent" (J. Sánchez-Ramos, C.L. Dávila-Fajardo, P. Toledo Frías, X. Díaz Villamarín, L.J. Martínez-González, S. Martínez Huertas, F. Burillo Gómez, J. Caballero Borrego, A. Bautista Pavés, M.C. Marín Guzmán, J.A. Ramirez Hernández, C. Correa Vilches, J. Cabeza Barrera, 2016) (1). This data article reports, for the first time, about the non-randomized clinical trial protocol that check if CYP2C19/ABCB1 genotype-guided strategy in which the choice of antiplatelet therapy is based on the genetic test, reduces the rates of cardiovascular events and bleeding compared to a non-tailored strategy in patients undergone percutaneous coronary intervention (PCI) with stent. The data included in this article are: design and setting of the study, study population, inclusion and exclusion criteria, definition of the intervention, objectives, variables (baseline characteristics and during the follow-up), study procedures, collection and treatment of the biological sample, genotyping, withdrawal criteria, sample size, statistic analysis, ethical aspects, information sheet and consent form. The authors confirm that this study has been registered in Eudra CT (Eudra CT: 2016-001294-33).
URI: http://hdl.handle.net/10668/2611
Versión del editor : http://www.sciencedirect.com/science/article/pii/S2352340916307806
DOI: 10.1016/j.dib.2016.12.019
ISSN : 2352-3409 (Online)
Appears in Collections:01- Artículos - GENYO. Centro Pfizer-Andalucía de Genómica e Investigación Oncológica
01- Artículos - ibsGRANADA. Instituto de Investigación Biosanitaria de Granada
01- Artículos - Complejo Hospitalario Universitario de Granada

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