Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/2641
Título : Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group
Autor : Franco Pérez, Fernando
Lavernia, Javier
Aguiar-Bujanda, David
Miramón, José
Gumá, Josep
Álvarez, Rut
Gómez-Codina, José
García Arroyo, Francisco
Llanos, Marta
Marin, Miguel
Alfaro, Jesus
Quero, Cristina
Delgado, Mayte
Nogales, Esteban
Menarguez, Francisco
Martinez, Natividad
Torrente, Maria
Royuela, Ana
Abreu, Delvys
Provencio, Mariano
Filiación: [Franco Pérez,F; Torrente,M; Provencio,M] Department of Medical Oncology, Hospital Universitario Puerta de Hierro, Majadahonda, Spain. [Lavernia,J] Department of Medical Oncology, Instituto Valenciano de Oncología, Valencia, Spain. [Aguiar-Bujanda,D] Department of Medical Oncology, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canarias, Spain. [Miramón,J] Department of Medical Oncology, Hospital Serranía de Ronda, Málaga, Spain. [Gumá,J] Department of Medical Oncology, Hospital Universitari Sant Joan de Reus, Reus, Spain. [Álvarez,R] Department of Medical Oncology, Hospital Universitario Virgen de la Salud, Toledo, Spain. [Gómez-Codina,J] Department of Medical Oncology, Hospital Universitari i Politècnic La Fe, Valencia, Spain. [García Arroyo,F] Department of Medical Oncology, Complejo Hospitalario de Pontevedra, Pontevedra, Spain. [Llanos,M] Department of Medical Oncology, Hospital Universitario de Canarias, San Cristóbal de La Laguna, Spain. [Marin,M] Department of Medical Oncology, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain. [Alfaro,J] Department of Medical Oncology, Instituto Oncológico de Kutxa, Donostia, Spain. [Quero,C] Department of Medical Oncology, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Delgado,M] Department of Medical Oncology, Hospital Universitario San Cecilio, Granada, Spain. [Nogales,E] Department of Medical Oncology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain. [Menarguez,F; Martinez,N] Department of Medical Oncology, Hospital General Universitario de Elche, Alicante, Spain. [Royuela,A] Department of Biostatistics, Hospital Universitario Puerta de Hierro, Majadahonda, Spain. [Abreu,D] Department of Medical Oncology, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canarias, Spain.
Palabras clave : Chemotherapy
Extranodal lymphoma
Immunotherapy
Lumpectomy
Neoplasms of the breast
Neoplasias de la mama
Consenso
Supervivencia sin rnfermedad
Inmunoterapia
Incidencia
Ganglios linfáticos
Linfoma
Linfoma no hodgkin
Glándulas mamarias humanas
MeSH: Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence
Medical Subject Headings::Anatomy::Tissues::Lymphoid Tissue::Lymph Nodes
Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Lymphatic Diseases::Lymphoproliferative Disorders::Lymphoma
Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Lymphatic Diseases::Lymphoproliferative Disorders::Lymphoma::Lymphoma, Non-Hodgkin
Medical Subject Headings::Anatomy::Body Regions::Breast::Mammary Glands, Human
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Remission Induction
Fecha de publicación : Mar-2017
Editorial : Elsevier
Cita Bibliográfica: Franco Pérez F, Lavernia J, Aguiar-Bujanda D, Miramón J, Gumá J, Álvarez R et al. Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group.Clin Lymphoma Myeloma Leuk. 2017 Mar;17(3):186-191.
Abstract: NTRODUCTION: Primary breast lymphoma is a rare form of localized extranodal lymphoma, which affects the mammary glands unilaterally or bilaterally, and can also affect the regional lymph nodes. MATERIALS AND METHODS: We reviewed 55 patients, with disease stages IE and IIE, diagnosed in 16 Spanish institutions between 1989 and 2016. A serial of clinical variables and treatment were collected, and overall survival (OS) and progression-free survival (PFS) were calculated. RESULTS: Of the 55 patients, 96.4% were women with an average age of 69 years. A total of 53 patients corresponded to non-Hodgkin lymphoma (NHL), of whom 36.3% had lymph node involvement upon diagnosis. Of the patients, 58.2% were stage IE, and 41.8% were stage IIE. Treatments received included radiotherapy (36.3%), chemotherapy (85.5%), and rituximab (in 38 of the 45 patients with NHL treated with chemotherapy). In all, 82.2% of complete responses were achieved. OS and progression-free survival at 5 years in NHL patients was 76% and 73%, respectively. CONCLUSION: Current treatments (chemotherapy, immunotherapy, and radiotherapy) achieve good control of the disease, with an OS of 5 years in 80% of the patients, although there is no consensus in treatment, given the scarce incidence of these lymphomas.
URI: http://hdl.handle.net/10668/2641
Versión del editor : http://www.sciencedirect.com/science/article/pii/S2152265016305602
DOI: 10.1016/j.clml.2016.09.004
ISSN : 2152-2669 (Online)
2152-2650 (Print)
Appears in Collections:01- Artículos - Hospital Virgen Macarena
01- Artículos - Hospital Virgen de la Victoria
01- Artículos - AGS Serranía de Málaga
01- Artículos - Complejo Hospitalario Universitario de Granada

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