Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/3077
Título : Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version
Autor : Blanco-Reina, Encarnación
García-Merino, Maria Rosa
Ocaña-Riola, Ricardo
Aguilar-Cano, Lorena
Valdellós, Jennifer
Bellido-Estévez, Inmaculada
Ariza-Zafra, Gabriel
Filiación: [Blanco-Reina,E; Bellido-Estévez,I] Pharmacology and Therapeutics Department, Medical School, Málaga Biomedical Institute (IBIMA), University of Málaga, Málaga, Spain. [García-Merino,MR] Health District of Córdoba Sur, Córdoba, Spain. [Ocaña-Riola,R] Statistics Department, Andalusian School of Public Health, Granada, Spain. [Aguilar-Cano,L] Health District of Málaga, Málaga, Spain. [Valdellós,J] Health Area of Málaga Norte, Málaga, Spain. [Ariza-Zafra,G] Geriatrics Department, University Hospital of Albacete, Albacete, Spain.
Palabras clave : Prescripciones de medicamentos
Prescripción inadecuada
Lista de medicamentos potencialmente inapropiados
Prevalencia
MeSH: Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Services::Pharmaceutical Services::Prescriptions::Drug Prescriptions
Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Services::Medical Errors::Medication Errors::Inappropriate Prescribing
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Polypharmacy
Medical Subject Headings::Diseases::Cardiovascular Diseases
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus
Fecha de publicación : 1-Dec-2016
Editorial : Public Library of Science
Cita Bibliográfica: Blanco-Reina E, García-Merino M, Ocaña-Riola R, Aguilar-Cano L, Valdellós J, Bellido-Estévez I, et al. Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version. PLOS ONE. 2016;11(12):e0167586. doi: 10.1371/journal.pone.0167586. PMID: 27907210; PMCID: PMC5132290.
Abstract: Emerging and changing evidence made it necessary to update STOPP-START criteria, and version 2 was published recently. In this study the objectives were to determine the prevalence of potentially inappropriate medication prescribing (PIM) in primary care using STOPP versions 1 (v1) and 2 (v2), as well as 2012 AGS Beers criteria, and analyze the factors associated with inappropriate prescribing according to STOPP/START v2. A cross-sectional study was carried out including community-dwelling older adults over the age of 65. Sociodemographic, clinical, functional and comprehensive drug therapy data were collected. The primary endpoint was the percentage of patients receiving at least one PIM. This variable was measured using three tools: STOPP v1, 2012 AGS Beers criteria and STOPP v2. Similarly, the percentage of patients receiving at least one potential prescribing omission (PPO) was calculated using START versions 1 and 2. A total of 1,615 prescriptions were reviewed. The median number of medications per patient was 7.1 drugs (±3.8). The prevalence of elderly people exposed to polypharmacy (≥5 medications) was 72.9%, whereas 28.4% of the participants took ≥10 drugs regularly. PIM were present in 18.7%, 37.3% and 40.4% of participants, according to the STOPP v1, 2012 Beers criteria and STOPP v2, respectively. According to STOPP v2, the number of medications taken (OR: 1.14, 1.06-1.25), the presence of a psychological disorder (OR: 2.22, 1.13-4.37) and insomnia (OR: 3.35, 1.80-6.32) were risk factors for taking a PIM. The prevalence of PPOs was 34.7% and 21.8% according to version 1 and 2, respectively. In conclusion, STOPP-START criteria have been remarkably modified, which is evidenced by the different prevalence rates detected using version 2, as compared to version 1. In fact, the level of agreement between version 1 and the updated version is only moderate. Special attention should be paid on benzodiazepines, which keep being the most frequent PIM.
URI: http://hdl.handle.net/10668/3077
Versión del editor : http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167586
DOI: 10.1371/journal.pone.0167586
ISSN : 1932-6203 (Online)
Appears in Collections:01- Artículos - DAP Córdoba Sur
01- Artículos - AGS Norte de Málaga
01- Artículos - DAP Málaga
01- Artículos - IBIMA. Instituto de Investigación Biomédica de Málaga
01- Artículos - EASP. Escuela Andaluza de Salud Pública

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