Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/3164
Title: Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis
Authors: Ercibengoa, María
Goenaga, Miguel Angel
Ardanuy, Carmen
Grau, Immaculada
García-de-la-Maria, Cristina
Almela, Manuel
Miro, Jose María
Navas, Enrique
Fariñas, María Carmen
Ruiz de Alegría, Carlos
de la Torre, Javier
Fernández, Fernando
Marín, Mercedes
Muñoz, Patricia
Orden, Beatriz
Oteo, José Antonio
García-Álvarez, Lara
de Alarcón, Arístides
Lepe Jiménez, José Antonio
Marimón, Jose María
metadata.dc.contributor.authoraffiliation: [Ercibengoa,M; Ardanuy,C; Grau,I; Marín,M; Muñoz,P; Marimón,JM] CIBER Enfermedades Respiratorias-CIBERES, Madrid, Spain. [Goenaga,MA] Servicio de Enfermedades Infecciosas, Hospital Universitario, Donostia, Spain. [Ardanuy,C] Servicio de Microbiologia, Hospital Universitari de Bellvitge. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), University of Barcelona, Barcelona, Spain. [Grau,I] Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge. Institut d’ Investigació Biomèdica de Bellvitge (IDIBELL), University of Barcelona, Barcelona, Spain. [García-de-la-Maria,C; Miro,JM] Servicio de Enfermedades Infecciosas, Hospital Clínic de Barcelona, Institut d’ Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. [Almela,M] Servicio de Microbiología, Hospital Clínic de Barcelona, Institut d’ Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. [Navas,E] Servicio de Enfermedades Infecciosas, Hospital Universitario Ramón y Cajal, Madrid, Spain. [Fariñas,MC] Servicio de Enfermedades Infecciosas, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain. [Ruiz de Alegría,C] Servicio de Microbiología, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain. [de la Torre,J] Grupo de Enfermedades Infecciosas de la Unidad de Medicina Interna, Hospital Costa del Sol, Marbella, Málaga, Spain. [Fernández,F] Servicio de Microbiología, Hospital Costa del Sol, Marbella, Málaga, Spain. [Marín,M; Muñoz,P] Departamento de Medicina, Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio, Marañón, Madrid, Spain. [Orden,B] Departamento de Microbiología, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain. [Oteo,JA; García-Álvarez,L] Departamento de Enfermedades Infecciosas, Hospital Universitario San Pedro, Logroño, La Rioja, Spain. [de Alarcón,A; Lepe Jiménez,JA] Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine. Infectious Diseases Research Group, Institute of Biomedicine of Seville (IBIS), University of Seville/CSIC/University Virgen del Rocío and Virgen Macarena, Sevilla, Spain. [Marimón,JM] Servicio de Microbiología, Hospital Universitario Donostia-IIS Biodonostia, San Sebastián, Spain.
Keywords: Streptococcus viridans;Infective endocarditis;Multicentre studies;Epidemiologic surveillance;Antibiotic resistance;Viridans streptococci;Estreptococos viridans;Endocarditis;Multicenter study;Estudio multicéntrico;Epidemiological monitoring;Monitoreo epidemiológico
metadata.dc.subject.mesh: Medical Subject Headings::Persons::Persons::Age Groups::Adult
Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged::Aged, 80 and over
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Bacteremia
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Endocarditis, Bacterial
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiological Monitoring
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Streptococcal Infections
Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Gram-Positive Cocci::Streptococcaceae::Streptococcus::Viridans Streptococci
Medical Subject Headings::Persons::Persons::Age Groups::Adult::Young Adult
Issue Date: 29-Mar-2019
Publisher: BioMed Central Ltd.
Citation: Ercibengoa M, Goenaga MA, Ardanuy C, Grau I, García-de-la-Maria C, Almela M, et al. Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis. BMC Infect Dis. 2019 Mar 29;19(1):291.
Abstract: Background: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. tigurinus among VGS endocarditis in Spain, and to compare the clinical characteristics and outcomes of endocarditis caused by S. tigurinus and other VGS. Methods: Retrospective nationwide study, performed between 2008 and 2016 in 9 Spanish hospitals from 7 different provinces comprising 237 cases of infective endocarditis. Streptococcal isolates were identified by sequencing fragments of their 16S rRNA, sodA and groEL genes. Clinical data of patients with streptococcal endocarditis were prospectively collected according to a pre-established protocol. Results: Patients with endocarditis represented 7/9 (77.8%) and 26/86 (30.2%) of the bacteraemias caused by S. tigurinus and other VGS, respectively (p < 0.001), in two of the hospital participants. Among patients with streptococcal endocarditis, 12 different Streptococcus species were recognized being S. oralis, S. tigurinus and S. mitis the three more common. No relevant statistical differences were observed in the clinical characteristics and outcomes of endocarditis caused by the different VGS species. Conclusions: In this multicenter study performed in Spain, S. tigurinus showed a higher predilection for the endocardial endothelium as compared to other VGS. However, clinical characteristics and outcomes of endocarditis caused by S. tigurinus did not significantly differ from endocarditis caused by other oral streptococci.
URI: http://hdl.handle.net/10668/3164
metadata.dc.relation.publisherversion: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-3914-6
metadata.dc.identifier.doi: 10.1186/s12879-019-3914-6
ISSN: 1471-2334 (Online)
Appears in Collections:01- Artículos - APES Costa del Sol
01- Artículos - IBIS. Instituto de Biomedicina de Sevilla

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