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Title: Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights
Authors: Rodríguez-Sojo, María Jesús
Ruiz-Malagón, Antonio Jesús
Rodríguez-Cabezas, María Elena
Gálvez, Julio
Rodríguez-Nogales, Alba
metadata.dc.contributor.authoraffiliation: [Rodríguez-Sojo,MJ; Ruiz-Malagón,AJ; Rodríguez-Cabezas,ME; Gálvez,J; Rodríguez-Nogales,A] CIBER-EHD, Center for Biomedical Research (CIBM), Department of Pharmacology, University of Granada, Granada, Spain. [Rodríguez-Sojo,MJ; Ruiz-Malagón,AJ; Rodríguez-Cabezas,ME; Gálvez,J; Rodríguez-Nogales,A] Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain. [Rodríguez-Nogales,A] Servicio de Digestivo, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Keywords: Probiotic;Limosilactobacillus fermentum CECT5716;Immunomodulation;Dysbiosis;Mechanisms of action;Gastrointestinal diseases;Microbiota;Probióticos;Inmunomodulación;Disbiosis;Mecanismos moleculares de acción farmacológica;Enfermedades gastrointestinales;Microbiota
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Dysbiosis
Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation
Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales::Lactobacillaceae
Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales
Medical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements::Probiotics
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Bacterial Proteins::Bacteriocins
Issue Date: 21-Mar-2021
Publisher: MDPI AG
Citation: Rodríguez-Sojo MJ, Ruiz-Malagón AJ, Rodríguez-Cabezas ME, Gálvez J, Rodríguez-Nogales A. Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights. Nutrients. 2021;13(3):1016.
Abstract: Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limosilactobacillus fermentum CECT5716 has become one of the most promising probiotics and it has been described to possess potential beneficial effects on inflammatory processes and immunological alterations. Different studies, preclinical and clinical trials, have evidenced its anti-inflammatory and immunomodulatory properties and elucidated the precise mechanisms of action involved in its beneficial effects. Therefore, the aim of this review is to provide an updated overview of the effect on host health, mechanisms, and future therapeutic approaches.
metadata.dc.identifier.doi: 10.3390/nu13031016
ISSN: 2072-6643 (Online)
Appears in Collections:01- Artículos - Hospital Virgen de las Nieves
01- Artículos - ibsGRANADA. Instituto de Investigación Biosanitaria de Granada

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