Please use this identifier to cite or link to this item:
Title: A new approach to the treatment of advanced heart failure: a case report
Authors: Robles-Mezcua, Ainhoa
Villaescusa-Catalán, José Manuel
Melero-Tejedor, José María
García-Pinilla, José Manuel
metadata.dc.contributor.authoraffiliation: [Robles-Mezcua,A; Villaescusa-Catalán,JM; Melero-Tejedor,JM; García-Pinilla,JM] Unidad de Gestión Clínica de Cardiología y Cirugía Cardiovascular, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Instituto de Biomedicina de Málaga (IBIMA), CIBER CV, Málaga, Spain.
Keywords: Arrhythmic events;Baroreceptor stimulating device;Case report;Decompensated;Heart failure;Arritmias cardíacas;Presorreceptores
metadata.dc.subject.mesh: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Cardiovascular::Heart Function Tests::Cardiac Output::Stroke Volume
Medical Subject Headings::Anatomy::Nervous System::Neurons::Neurons, Afferent::Sensory Receptor Cells::Mechanoreceptors::Pressoreceptors
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathological Conditions, Anatomical::Ventricular Remodeling
Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Ventricular Function::Ventricular Function, Left
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Mortality::Mortality, Premature
Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Failure
Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression
Issue Date: 2021
Publisher: Oxford University Press on behalf of the European Society of Cardiology
Citation: Robles-Mezcua A, Villaescusa-Catalán JM, Melero-Tejedor JM, García-Pinilla JM. A new approach to the treatment of advanced heart failure: a case report. Eur Heart J Case Rep. 2021 Jan 12;5(2):ytaa541
Abstract: Background: Autonomic imbalance characterized by sympathetic predominance and decreased parasympathetic transmission is a classic feature of heart failure (HF) with reduced left ventricular ejection fraction, leading to disease progression, exercise intolerance, ventricular remodelling, arrhythmias, and premature death. The underlying mechanisms to these processes are not yet fully understood, but the current treatments influence this dysregulation, towards an inhibition of sympathetic hyperactivation. New therapies, such as the stimulation of carotid baroreceptors, enhance this inhibition to restore autonomic balance and to be able to cope with these mechanisms. Case summary: We report the case of a 76-year-old male with advanced HF at an advanced stage, refractory to optimal treatment, and included in a programme of ambulatory infusions of Levosimendan as compassionate treatment. The patient presented with multiple episodes of decompensated HF secondary to ventricular arrhythmias. A multidisciplinary team decided to implant a baroreceptor stimulator device (Barostim Neo) in order to improve HF symptoms and quality of life, as well as trying to decrease the burden of arrhythmias. The procedure was performed with no complications and good therapeutic response, resulting in a significant reduction of arrhythmias. Discussion: Treatment with a baroreceptor stimulating device is presented as a safe and effective option in our patients with advanced HF refractory to conventional treatment, to improve their quality of life and reduce symptoms; in addition to appearing as a promising option in those with arrhythmic events, which are difficult to control with usual treatments and procedures.
metadata.dc.identifier.doi: 10.1093/ehjcr/ytaa541
ISSN: 2514-2119 (Online)
Appears in Collections:01- Artículos - IBIMA. Instituto de Investigación Biomédica de Málaga

Files in This Item:
File Description SizeFormat 
ANewApproach_RoblesMezcua.pdfArtículo original838,25 kBAdobe PDFView/Open
ANewApproach_RoblesMezcua_MaterialSuplementario_1.pptxPresentación1,83 MBMicrosoft Powerpoint XMLView/Open
ANewApproach_RoblesMezcua_MaterialSuplementario_2.aviVídeo23,83 MBAudio Video Interleave FileView/Open
ANewApproach_RoblesMezcua_MaterialSuplementario_3.aviVídeo9,25 MBAudio Video Interleave FileView/Open

This item is protected by original copyright

This item is licensed under a Creative Commons License Creative Commons