Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/374
Title: Necrotising pneumonia due to influenza A (H1N1) and community-acquired methicillin-resistant Staphylococcus aureus clone USA300: successful management of the first documented paediatric case.
Authors: Obando, I.
Valderrabanos, ES.
Millan, JA.
Neth, OW.
metadata.dc.contributor.authoraffiliation: [Obando,I; Neth,OW] Department of Paediatric Infectious Diseases and Immunology, Hospital Universitario Virgen del Rocio, Seville, Spain. [Valderrabanos,ES; Millan,JA] Department of Paediatric Intensive Care, Hospital Universitario Virgen del Rocio, Seville, Spain.
Keywords: Neumonía Viral;Neumonía Bacteriana;Subtipo H1N1 del Virus de la Influenza A;Staphylococcus aureus Resistente a Meticilina;Niño
metadata.dc.subject.mesh: Medical Subject Headings::Diseases::Virus Diseases::Pneumonia, Viral
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Pneumonia, Bacterial
Medical Subject Headings::Organisms::Viruses::RNA Viruses::Orthomyxoviridae::Influenzavirus A::Influenza A virus::Influenza A Virus, H1N1 Subtype
Medical Subject Headings::Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Staphylococcaceae::Staphylococcus::Staphylococcus aureus::Methicillin-Resistant Staphylococcus aureus
Medical Subject Headings::Named Groups::Persons::Age Groups::Child
Medical Subject Headings::Diseases::Respiratory Tract Diseases::Respiratory Tract Infections::Influenza, Human
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Staphylococcal Infections
Issue Date: Apr-2010
Publisher: BMJ Publishing Group
Citation: Obando I, Valderrabanos ES, Millan JA, Neth OW. Necrotising pneumonia due to influenza A (H1N1) and community-acquired methicillin-resistant Staphylococcus aureus clone USA300: successful management of the first documented paediatric case. Arch Dis Child. 2010 Apr;95(4):305-6.
Abstract: Necrotising pneumonia in young, previously healthy patients due to Panton–Valentine leucocidin (PVL) producing Staphylococcus aureus has been increasingly recognised. PVL pneumonia is often associated with influenza co-infection and high mortality. This case report describes the successful management of the first documented paediatric case of a previous healthy adolescent who developed necrotising pneumonia due to community-acquired methicillin-resistant (CA-MRSA) clone USA300 with pandemic influenza A (H1N1) co-infection, and highlights the importance of early recognition and initiation of appropriate therapy for this potentially fatal co-infection. PCR remains the gold standard to diagnose pandemic H1N1 since it may not be detected by rapid antigen tests. Bacterial necrotising pneumonia should be suspected in those presenting with worsening flu-like symptoms and clinical and/or radiological evidence of PVL infection (multifocal infiltrates, effusion and cavitation). These patients may benefit from the administration of toxin neutralising agents. In light of the current H1N1 pandemic, healthcare professionals will be increasingly confronted with this clinical scenario.
Description: Case report. Not externally peer reviewed
URI: http://hdl.handle.net/10668/374
metadata.dc.relation.publisherversion: http://adc.bmj.com/content/95/4/305.long
metadata.dc.identifier.doi: 10.1136/adc.2009.175281
ISSN: 1468-2044 (Online)
0003-9888 (Print)
Appears in Collections:01- Artículos - Hospital Virgen del Rocío

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