Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/444
Title: Estudio transversal sobre la prevalencia de la Enfermedad Metabólica Ósea (EMO) y Nutrición Parenteral Domiciliaria (NPD) en España: datos del Grupo NADYA
Transversal study on the prevalence of Metabolic Bone Disease (MBD) and Home Parenteral Nutrition (HPN) in Spain: data from NADYA group
Authors: Martínez, C.
Virgili, N.
Cuerda, C.
Chicharro, L.
Gómez, P.
Moreno, J.M.
Alvarez, J.
Martí, E.
Matía, P
Penacho, M.A.
Garde, C.
De Luis, D.
Gonzalo, M.
Lobo, G.
metadata.dc.contributor.authoraffiliation: [Martínez,C; Gómez,P] Hospital Universitario Central de Asturias, Oviedo. [Virgili,N] Hospital de Bellvitge, Hospitalet de Llobregat. [Cuerda,C] Hospital Gregorio Marañón, Madrid. [Chicharro, L] Hospital Vall d'Hebrón, Barcelona. [Moreno,JM] Hospital 12 de Octubre, Madrid. [Álvarez,J] Hospital Príncipe de Asturias, Alcalá de Henares, Madrid. [Martí,E] Hospital General de Valencia. [Matía,P] Hospital Clínico de Madrid. [Penacho,MA] Hospital del Bierzo, León. [Garde,C] Hospital de Donostia. [De Luis,D] Hospital Universitario Río Ortega, Valladolid. [Gonzalo,M] Hospital Universitario Carlos Haya, Málaga. [Lobo,G] Hospital Universitario Virgen de las Nieves, Granada, España.
metadata.dc.contributor.group: NADYA-SENPE
metadata.dc.subject.mesh: Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density
Medical Subject Headings::Diseases::Musculoskeletal Diseases::Bone Diseases::Bone Diseases, Metabolic
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Photometry::Densitometry
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutritional Status
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Nutritional Support
Medical Subject Headings::Diseases::Musculoskeletal Diseases::Bone Diseases::Bone Diseases, Metabolic::Osteoporosis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Nutritional Support::Parenteral Nutrition::Parenteral Nutrition, Home
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Retrospective Studies
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition::Deficiency Diseases::Avitaminosis::Vitamin D Deficiency
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult
Issue Date: Nov-2010
Publisher: Grupo Aula Médica, S.L.
Citation: Martínez C, Virgili N, Cuerda C, Chicharro L, Gómez P, Moreno JM, et al. Estudio transversal sobre la prevalencia de la Enfermedad Metabólica Ósea (EMO) y Nutrición Parenteral Domiciliaria (NPD) en España: datos del Grupo NADYA. Nutr Hosp. 2010;25(6):920-4.
Abstract: Patients with intestinal failure who receive HPN are at high risk of developing MBD. The origin of this bone alteration is multifactorial and depends greatly on the underlying disease for which the nutritional support is required. Data on the prevalence of this disease in our environment is lacking, so NADYA-SEMPE group has sponsored this transversal study with the aim of knowing the actual MBD prevalence. MATERIAL AND METHODS: Retrospective data from 51 patients from 13 hospitals were collected. The questionnaire included demographic data as well as the most clinically relevant for MBD data. Laboratory data (calciuria, PTH, 25 -OH -vitamin D) and the results from the first and last bone densitometry were also registered. RESULTS: Bone mineral density had only been assessed by densitometry in 21 patients at the moment HPN was started. Bone quality is already altered before HPN in a significant percentage of cases (52%). After a mean follow up of 6 years, this percentage increases up to 81%. Due to retrospective nature of the study and the low number of subjects included it has not been possible to determine the role that HPN plays in MBD etiology. Only 35% of patients have vitamin D levels above the recommended limits and the majority of them is not on specific supplementation. CONCLUSIONS: HPN is associated with very high risk of MBD, therefore, management protocols that can lead to early detection of the problem as well as guiding for follow up and treatment of these patients are needed.
metadata.dc.description.otherabstracts: Los pacientes con insuficiencia intestinal que reciben NPD presentan un elevado riesgo de presentar EMO. El origen de esta afectación ósea es multifactorial y depende en gran parte de la enfermedad de base que origina la necesidad del soporte. En nuestro medio no disponemos de datos acerca de la prevalencia de esta enfermedad, por lo que el grupo NADYA-SENPE ha patrocinado este estudio transversal para intentar conocer la prevalencia de la EMO. Material y métodos: Se han recogido datos retrospectivos de 51 pacientes pertenecientes a 13 hospitales. La encuesta realizada incluía datos demográficos y los datos clínicos más relevantes que pudieran influir en la aparición de EMO. También se han registrados los datos analíticos más significativos para este proceso (calciuria, PTH, 25 OH vitamina D) y los resultados de la primera y la última densitometría realizadas. Resultados: Solamente 21 pacientes tenían realizada una densitometría en el momento de iniciar la NPD. La calidad del hueso está alterada al inicio de la NPD en un porcentaje significativo de casos (52%) Tras un seguimiento medio de 6 años ese porcentaje se eleva hasta el 81%. Dado el carácter retrospectivo del estudio y el escaso número de sujetos no es posible determinar el papel que juega la NPD en la etiología de la EMO. Sólo un 35% de los pacientes presentan niveles de vitamina D por encima de los niveles recomendados y la mayoría de ellos no recibe suplementación específica. Conclusiones: La NPD se asocia a un riesgo muy elevado de presentar EMO, por tanto es necesario disponer de protocolos de actuación que permitan detectar precozmente este problema y orientar el seguimiento y tratamiento de estos pacientes.
URI: http://hdl.handle.net/10668/444
metadata.dc.relation.publisherversion: http://www.nutricionhospitalaria.com/mostrarrevista.asp?id=345
metadata.dc.identifier.doi: 10.3305/nh.2010.25.6.4645
ISSN: 0212-1611 (Print)
1699-5198 (Online)
Appears in Collections:01- Artículos - Hospital Regional de Málaga
01- Artículos - Hospital Virgen de las Nieves

Files in This Item:
File Description SizeFormat 
Martinez_EstudioTransversalSobre.pdfArtículo principal84,32 kBAdobe PDFView/Open


This item is protected by original copyright



This item is licensed under a Creative Commons License Creative Commons