Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/468
Title: Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study.
Potenciais fatores de risco para o desenvolvimento de esclerose múltipla no Rio de Janeiro: um estudo caso controle
Authors: Silva, Kátia Regina Penha da
Papais Alvarenga, Regina Maria
Fernandez Y Fernandez, Oscar
Alvarenga, Hélcio
Santos Thuler, Luiz Claudio
metadata.dc.contributor.authoraffiliation: [Penha da Silva, KR; Papais Alvarenga,RM] Neurology Department, Hospital da Lagoa, Federal University of the State of Rio de Janeiro(UNIRIO)Rio de Janeiro RJ,Brazil. [Penha da Silva, KR; Papais Alvarenga,RM; Alvarenga,H; Santos Thuler, LC] Postgraduate Master Program in Neurology, Federal University of the State of Rio de Janeiro(UNIRIO) Rio de Janeiro RJ,Brazil. [Fernandez y Fernandez,O] Neurology Department, Carlos Haya Teaching Hospital, Malaga, Spain.
Keywords: Immunization;Tobacco;Single person;Consumption of animal brain;Esclerosis Múltiple;Factores de Riesgo;Inmunización;Tabaco
metadata.dc.subject.mesh: Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis::Multiple Sclerosis, Chronic Progressive
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
Medical Subject Headings::Geographicals::Geographic Locations::Americas::South America::Brazil
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Check Tags::Male
Issue Date: Jun-2009
Publisher: Academia Brasileira de Neurologia - ABNEURO
Citation: Silva KRP da, Alvarenga RMP, Fernandez Y Fernandez O, Alvarenga H, Santos Thuler LC. Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study. Arq. Neuro-Psiquiatr. 2009 Jun;67(2A):229-34
Abstract: PURPOSE. To evaluate potential risk factors for the development of multiple sclerosis in Brazilian patients. METHOD. A case control study was carried out in 81 patients enrolled at the Department of Neurology of the Hospital da Lagoa in Rio de Janeiro, and 81 paired controls. A standardized questionnaire on demographic, social and cultural variables, and medical and family history was used. Statistical analysis was performed using descriptive statistics and conditional logistic regression models with the SPSS for Windows software program. RESULTS. Having standard vaccinations (vaccinations specified by the Brazilian government) (OR=16.2; 95% CI=2.3-115.2), smoking (OR=7.6; 95% CI=2.1-28.2), being single (OR=4.7; 95% CI=1.4-15.6) and eating animal brain (OR=3.4; 95% CI=1.2-9.8) increased the risk of developing MS. CONCLUSIONS. RESULTS of this study may contribute towards better awareness of the epidemiological characteristics of Brazilian patients with multiple sclerosis.
metadata.dc.description.otherabstracts: [Port]Resumo – Objetivo: Avaliar os potenciais fatores de risco para o desenvolvimento de esclerose múltipla em pacientes brasileiros. Método: Um estudo caso-controle incluiu 81 pacientes atendidos no Departamento de Neurologia do Hospital da Lagoa, no Rio de Janeiro, e 81 controles. Um questionário padronizado incluiu variáveis demográficas, sociais e culturais, além da história familiar e clínica. A análise dos dados foi realizada por meio do programa SPSS para Windows e foi constituída de estatísticas descritivas e de um modelo de regressão logística condicional. Resultados: Pacientes com história de imunização (OR=16,2; IC95%=2,3–115,2), fumantes (OR=7,6; IC95%=2,1–28,2), solteiros (OR=4,7; IC95%=1,4–15,6) e que consumiam cérebro de animal (OR=3,4; IC95%=1,2–9,8) tiveram risco mais elevado de desenvolver esclerose múltipla quando comparados aos controles. Conclusão: Os resultados deste estudo podem contribuir para um melhor entendimento das características epidemiológicas dos pacientes brasileiros com esclerose múltipla.
URI: http://hdl.handle.net/10668/468
metadata.dc.relation.publisherversion: http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-282X2009000200011&lng=es&nrm=iso&tlng=en
metadata.dc.identifier.doi: 10.1590/S0004-282X2009000200011
ISSN: 1678-4227(Online)
0004-282X (Print)
Appears in Collections:01- Artículos - Hospital Regional de Málaga

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