Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/609
Title: Clinical presentation and time-course of postoperative venous thromboembolism: Results from the RIETE Registry
Authors: Arcelus, Juan Ignacio
Monreal, Manuel
Caprini, Joseph A
Gutiérrez Guisado, Javier
Soto, Mª José
Núñez, Manuel Jesús
Alvárez, Juan Carlos
metadata.dc.contributor.authoraffiliation: [Arcelus,JI] Departamento de Cirugía de la Universidad de Granada y Hospital Virgen de las Nieves, Granada, Spain. [Monreal,M] Servicio de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. [Caprini,JA] Department of Surgery, Evanston Northwestern Healthcare, Evanston, Illinois,USA. [Gutiérrez Guisado,J] Servicio de Medicina Interna, Hospital Asepeyo Coslada, Madrid, Spain. [Soto,MJ] Servicio de Medicina Interna, Hospital Universitario Puerta del Mar, Cádiz, Spain. [Núñez,MJ] Servicio de Medicina Interna, Hospital Comarcal de Salnés, Pontevedra, Spain.[Alvárez,JC] Servicio de Medicina Interna, Hospital Virgen de Macarena, Sevilla, Spain.
metadata.dc.contributor.group: RIETE investigators
Keywords: Ancianos;Argentina;Europa ( Continente);Femenino;Fibrinolíticos;Hemorragia;Humanos;Incidencia;Israel;Masculino;Mediana edad;Neoplasias;Procedimientos ortopédicos;Estudios prospectivos;Embolia pulmonar;Recurrencia local de neoplasia;Sistema de registros;Procedimientos quirúrgicos;Factores de tiempo;Tromboembolia venosa;Surgery;Venous thromboembolism
metadata.dc.subject.mesh: Medical Subject Headings::Geographicals::Geographic Locations::Americas::South America::Argentina
Medical Subject Headings::Geographicals::Geographic Locations::Europe
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Fibrin Modulating Agents::Fibrinolytic Agents
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Hemorrhage
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence
Medical Subject Headings::Geographicals::Geographic Locations::Asia::Asia, Western::Middle East::Israel
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Diseases::Neoplasms
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Orthopedic Procedures
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies
Medical Subject Headings::Diseases::Respiratory Tract Diseases::Lung Diseases::Pulmonary Embolism
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Registries
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors
Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Embolism and Thrombosis::Thromboembolism::Venous Thromboembolism
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
Issue Date: 3-Mar-2008
Publisher: Schattauer
Citation: Arcelus JI, Monreal M, Caprini JA, Gutiérrez Guisado J, Soto MJ, Núñez MJ et al. Clinical presentation and time-course of postoperative venous thromboembolism: Results from the RIETE Registry.Thromb Haemost. 2008 Mar;99(3):546-51
Abstract: There is little literature about the clinical presentation and time-course of postoperative venous thromboembolism (VTE) in different surgical procedures. RIETE is an ongoing, prospective registry of consecutive patients with objectively confirmed, symptomatic acute VTE. In this analysis, we analysed the baseline characteristics, thromboprophylaxis and therapeutic patterns, time-course, and three-month outcome of all patients with postoperative VTE. As of January 2006, there were 1,602 patients with postoperative VTE in RIETE: 393 (25%) after major orthopaedic surgery (145 elective hip arthroplasty, 126 knee arthroplasty, 122 hip fracture); 207 (13%) after cancer surgery; 1,002 (63%) after other procedures. The percentage of patients presenting with clinically overt pulmonary embolism (PE) (48%, 48%, and 50% respectively), the average time elapsed from surgery to VTE (22 +/- 16, 24 +/- 16, and 21 +/- 15 days, respectively), and the three-month incidence of fatal PE (1.3%, 1.4%, and 0.8%, respectively), fatal bleeding (0.8%, 1.0%, and 0.2%, respectively), or major bleeding (2.3%, 2.9%, and 2.8%, respectively) were similar in the three groups. However, the percentage of patients who had received thromboprophylaxis (96%, 76% and 52%, respectively), the duration of prophylaxis (17 +/- 9.6, 13 +/- 8.9, and 12 +/- 11 days, respectively) and the mean daily doses of low-molecular-weight heparin (4,252 +/- 1,016, 3,260 +/- 1,141, and 3,769 +/- 1,650 IU, respectively), were significantly lower in those undergoing cancer surgery or other procedures. In conclusion, the clinical presentation, time-course, and three-month outcome of VTE was similar among the different subgroups of patients, but the use of prophylaxis in patients undergoing cancer surgery or other procedures was suboptimal.
Description: Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't;
URI: http://hdl.handle.net/10668/609
metadata.dc.relation.publisherversion: http://www.schattauer.de/en/magazine/subject-areas/journals-a-z/thrombosis-and-haemostasis/contents/archive/issue/348/manuscript/9460.html
metadata.dc.identifier.doi: 10.1160/TH07-10-0611
ISSN: 0340-6245 (Print)
Appears in Collections:01- Artículos - Hospital Puerta del Mar
01- Artículos - Hospital Virgen de las Nieves
01- Artículos - Hospital Virgen Macarena

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