Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/655
Title: Diagnostic accuracy of the Eurotest for dementia: a naturalistic, multicenter phase II study
Authors: Carnero-Pardo, Cristobal
Gurpegui, Manuel
Sanchez-Cantalejo, Emilio
Frank, Ana
Mola, Santiago
Barquero, M Sagrario
Montoro-Rios, M Teresa
metadata.dc.contributor.authoraffiliation: [Carnero-Pardo,C; Montoro-Rios,MT] Hospital Universitario Virgen de las Nieves, Granada, Spain. [Gurpegui,M] Department of Psychiatry and Institute of Neurosciences, Universidad de Granada, Spain. [Sanchez-Cantalejo,E] Escuela Andaluza de Salud Pública, Granada, Spain. [Frank,A] Hospital Universitario La Paz, Madrid, Spain. [Mola,S] Hospital Vega Baja, Orihuela, Alicante, Spain. [Barquero,MS] Hospital Clínico San Carlos, Madrid, Spain.
metadata.dc.contributor.group: The Trans-EUROTEST Group
Keywords: Anciano;Anciano de 80 o más Años;Estudios Transversales;Demencia;Escolaridad;Europa (Continente);Femenino;Administración Financiera;Humanos;Modelos Logísticos;Masculino;Mediana Edad;Pruebas Psicológicas;Curva ROC;Reproducibilidad de Resultados;Sensibilidad y Especificidad
metadata.dc.subject.mesh: Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged::Aged, 80 and over
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies
Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Dementia
Medical Subject Headings::Health Care::Population Characteristics::Socioeconomic Factors::Educational Status
Medical Subject Headings::Geographicals::Geographic Locations::Europe
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Health Care::Health Care Economics and Organizations::Economics::Financial Management
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Logistic Models
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Sensitivity and Specificity::ROC Curve
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Sensitivity and Specificity
Medical Subject Headings::Health Care::Population Characteristics::Socioeconomic Factors
Medical Subject Headings::Check Tags::Female
Issue Date: 10-Apr-2006
Publisher: BioMed Central
Citation: Carnero-Pardo C, Gurpegui M, Sanchez-Cantalejo E, Frank A, Mola S, Barquero NS et al. Diagnostic accuracy of the Eurotest for dementia: a naturalistic, multicenter phase II study. BMC Neurol. 2006 Apr 10;6:15.
Abstract: BACKGROUND Available screening tests for dementia are of limited usefulness because they are influenced by the patient's culture and educational level. The Eurotest, an instrument based on the knowledge and handling of money, was designed to overcome these limitations. The objective of this study was to evaluate the diagnostic accuracy of the Eurotest in identifying dementia in customary clinical practice. METHODS A cross-sectional, multi-center, naturalistic phase II study was conducted. The Eurotest was administered to consecutive patients, older than 60 years, in general neurology clinics. The patients' condition was classified as dementia or no dementia according to DSM-IV diagnostic criteria. We calculated sensitivity (Sn), specificity (Sp) and area under the ROC curves (aROC) with 95% confidence intervals. The influence of social and educational factors on scores was evaluated with multiple linear regression analysis, and the influence of these factors on diagnostic accuracy was evaluated with logistic regression. RESULTS Sixteen neurologists recruited a total of 516 participants: 101 with dementia, 380 without dementia, and 35 who were excluded. Of the 481 participants who took the Eurotest, 38.7% were totally or functionally illiterate and 45.5% had received no formal education. Mean time needed to administer the test was 8.2+/-2.0 minutes. The best cut-off point was 20/21, with Sn = 0.91 (0.84-0.96), Sp = 0.82 (0.77-0.85), and aROC = 0.93 (0.91-0.95). Neither the scores on the Eurotest nor its diagnostic accuracy were influenced by social or educational factors. CONCLUSION This naturalistic and pragmatic study shows that the Eurotest is a rapid, simple and useful screening instrument, which is free from educational influences, and has appropriate internal and external validity.
Description: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Validation Studies;
URI: http://hdl.handle.net/10668/655
metadata.dc.relation.publisherversion: http://www.biomedcentral.com/1471-2377/6/15
metadata.dc.identifier.doi: 10.1186/1471-2377-6-15
ISSN: 1471-2377 (Online)
Appears in Collections:01- Artículos - Hospital Virgen de las Nieves

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