Please use this identifier to cite or link to this item: http://hdl.handle.net/10668/718
Título : Validation of a new tool to assess health-related quality of life in psoriasis: the PSO-LIFE questionnaire.
Autor : Dauden, Esteban
Herrera Acosta, Enrique
Puig, Lluis
Sánchez-Carazo, José Luis
Toribio, Jaime
Caloto, Ma Teresa
Nocea, Gonzalo
Roset, Montse
Lara, Nuria
Filiación: [Dauden,E] Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain. [Herrera Acosta,E] Department of Dermatology, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Puig,Ll] Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. [Sánchez-Carazo,JL] Department of Dermatology, Hospital General de Valencia, Valencia, Spain. [Toribio,J] Department of Dermatology, CHU Santiago (Hospital Gil Casares), Santiago de Compostela, Spain. [Lara,N] IMS Health, Health Economics and Outcomes Research, Barcelona, Spain.
Palabras clave : Anciano
Anciano de 80 o más Años
Análisis de Varianza
Estudios de Seguimiento
Indicadores de Salud
Visita a Consultorio Médico
Evaluación de Resultado (Atención de Salud)
Psicometría
Investigación Cualitativa
Calidad de Vida
Reproducibilidad de Resultados
Clase social
España
Estadísticas no Paramétricas
MeSH: Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged::Aged, 80 and over
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Analysis of Variance
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Follow-Up Studies
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Data Collection::Health Surveys::Health Status Indicators
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Health Care::Health Services Administration::Organization and Administration::Professional Practice::Office Visits
Medical Subject Headings::Health Care::Health Services Administration::Quality of Health Care::Outcome and Process Assessment (Health Care)::Outcome Assessment (Health Care)
Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases, Papulosquamous::Psoriasis
Medical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Psychometrics
Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Science::Research::Empirical Research::Qualitative Research
Medical Subject Headings::Humanities::Humanities::Philosophy::Life::Quality of Life
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results
Medical Subject Headings::Health Care::Population Characteristics::Socioeconomic Factors::Social Class
Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Statistics, Nonparametric
Fecha de publicación : 24-May-2012
Editorial : BioMed Central
Cita Bibliográfica: Dauden E, Herrera E, Puig L, Sánchez-Carazo JL, Toribio J, Caloto MT, et al. Validation of a new tool to assess health-related quality of life in psoriasis: the PSO-LIFE questionnaire. Health Qual Life Outcomes. 2012; 10(1):56
Abstract: BACKGROUND Several questionnaires have been used to measure health related quality of life (HRQoL) in patients with psoriasis, few have been adapted for use in Spain; none of them was developed specifically for the Spanish population. The purpose of the study was to validate and assess the sensitivity to change of a new questionnaire to measure HRQOL in patients with psoriasis (PSO-LIFE). METHODS Observational, prospective, multicenter study performed in centers around Spain. Patients with active or inactive psoriasis completed the PSO-LIFE together with other Dermatology Quality of Life Index (DLQI) and Psoriasis Disability Index (PDI). A control group of patients with urticaria or atopic dermatitis was also included. Internal consistency and test-retest reliability of the PSO-LIFE were assessed by calculating Cronbach's alpha and Intraclass Correlation Coefficient (ICC). Validity was assessed by examining factorial structure, the capacity to discriminate between groups, and correlations with other measures. Sensitivity to change was measured using effect sizes. RESULTS The final sample included for analysis consisted of 304 patients and 56 controls. Mean (SD) age of psoriasis patients was 45.3 (14.5) years compared to 38.8 (14) years for controls (p < 0.01). Cronbach's alpha for the PSO-LIFE was 0.95 and test-retest reliability using the ICC was 0.98. Factor analysis showed the questionnaire to be unidimensional. Mean (SD) PSO-LIFE scores differed between patients with psoriasis and controls (64.9 [22.5] vs 69.4 [17.3]; p < 0.05), between those with active and inactive disease (57.4 [20.4] vs 76.4 [20.6]; p < 0.01), and between those with visible and non-visible lesions (63.0 [21.9] vs. 74.8 [23.9]; p < 0.01). The correlation between PSO-LIFE and PASI scores was moderate (r = -0.43) while correlations with DLQI and PDI dimensions ranged from moderate to high (between 0.4 and 0.8). Effect size on the PSO-LIFE in patients reporting 'much improved' health status at study completion was 1.01 (large effect size). CONCLUSIONS The present results provide substantial support for the reliability, validity, and responsiveness of the PSO-LIFE questionnaire in the population for which it was designed.
Descripción : Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Validation Studies;
URI: http://hdl.handle.net/10668/718
Versión del editor : http://www.hqlo.com/content/10/1/56
DOI: 10.1186/1477-7525-10-56
ISSN : 1477-7525 (Online)
Appears in Collections:01- Artículos - Hospital Virgen de la Victoria

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