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Title: Incidence and clinical impact of infective endocarditis after transcatheter aortic valve implantation.
Authors: Martínez-Sellés, Manuel
Bouza, Emilio
Díez-Villanueva, Pablo
Valerio, Maricela
Fariñas, María Carmen
Muñoz-García, Antonio J
Ruiz-Morales, Josefa
Gálvez-Acebal, Juan
Antorrena, Isabel
de la Hera Galarza, Jesús María
Navas, Enrique
Muñoz, Patricia
GAMES study group
metadata.dc.subject.mesh: Aged
Aged, 80 and over
Aortic Valve Stenosis
Endocarditis, Bacterial
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Prospective Studies
Prosthesis-Related Infections
Transcatheter Aortic Valve Replacement
Treatment Outcome
Issue Date: 2016
Abstract: To describe the characteristics of infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI). This study was performed using the GAMES database, a national prospective registry of consecutive patients with IE in 26 Spanish hospitals. Of the 739 cases of IE diagnosed during the study, 1.3% were post-TAVI IE, and these 10 cases, contributed by five centres, represented 1.1% of the 952 TAVIs performed. Mean age was 80 years. All valves were implanted transfemorally. IE appeared a median of 139 days after implantation. The mean age-adjusted Charlson comorbidity index was 5.45. Chronic kidney disease was frequent (five patients), as were atrial fibrillation (five patients), chronic obstructive pulmonary disease (four patients), and ischaemic heart disease (four patients). Six patients presented aortic valve involvement, and four only mitral valve involvement; the latter group had a higher percentage of prosthetic mitral valves (0% vs. 50%). Vegetations were found in seven cases, and four presented embolism. One patient underwent surgery. Five patients died during follow-up: two of these patients died during the admission in which the valve was implanted. IE is a rare but severe complication after TAVI which affects about 1% of patients and entails a relatively high mortality rate. IE occurred during the first year in nine of the 10 patients.
metadata.dc.identifier.doi: 10.4244/EIJY15M02_05
Appears in Collections:Producción 2020

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