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|Title:||Conventional Matrices Loaded Onto a Graphene Layer Enhances MALDI-TOF/TOF Signal: Its Application to Improve Detection of Phosphorylated Peptides.|
|Authors:||Rodríguez, Carlos E|
Urdiales, José Luis
Le Guével, Xavier
Signal Processing, Computer-Assisted
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
|Abstract:||This is the first study where graphene is used as a MALDI adjuvant in combination with the traditional matrix α-cyano-4-hydroxycinnamic acid (CHCA) to improve the signal intensity of peptide samples. Use of this amended matrix not only leads to increased signals but also to a higher number of peaks detected in complex samples. Additionally, the use of graphene has a stabilizing effect that can also be exploited to improve the detection of easily cleavable molecules. Graphical Abstract ᅟ.|
|Appears in Collections:||Producción 2020|
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