Please use this identifier to cite or link to this item:
Title: Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: A CHAID decision-tree analysis.
Authors: Rodríguez, Alejandro H
Avilés-Jurado, Francesc X
Díaz, Emili
Schuetz, Philipp
Trefler, Sandra I
Solé-Violán, Jordi
Cordero, Lourdes
Vidaur, Loreto
Estella, Ángel
Pozo Laderas, Juan C
Socias, Lorenzo
Vergara, Juan C
Zaragoza, Rafael
Bonastre, Juan
Guerrero, José E
Suberviola, Borja
Cilloniz, Catia
Restrepo, Marcos I
Martín-Loeches, Ignacio
Keywords: CHAID analysis;Community-acquired pneumonia;Influenza A(H1N1)pmd;Procalcitonin;Prognosis;Respiratory coinfection;Septic shock
metadata.dc.subject.mesh: Adult
Bacterial Infections
Calcitonin Gene-Related Peptide
Decision Trees
Influenza, Human
Intensive Care Units
Middle Aged
Predictive Value of Tests
Prospective Studies
Protein Precursors
Sensitivity and Specificity
Issue Date: 15-Dec-2015
Abstract: To define which variables upon ICU admission could be related to the presence of coinfection using CHAID (Chi-squared Automatic Interaction Detection) analysis. A secondary analysis from a prospective, multicentre, observational study (2009-2014) in ICU patients with confirmed A(H1N1)pdm09 infection. We assessed the potential of biomarkers and clinical variables upon admission to the ICU for coinfection diagnosis using CHAID analysis. Performance of cut-off points obtained was determined on the basis of the binominal distributions of the true (+) and true (-) results. Of the 972 patients included, 196 (20.3%) had coinfection. Procalcitonin (PCT; ng/mL 2.4 vs. 0.5, p  PCT has a high negative predictive value (94%) and lower PCT levels seems to be a good tool for excluding coinfection, particularly for patients without shock.
metadata.dc.identifier.doi: 10.1016/j.jinf.2015.11.007
Appears in Collections:Producción 2020

Files in This Item:
There are no files associated with this item.

This item is protected by original copyright

This item is licensed under a Creative Commons License Creative Commons