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Title: Realistic aortic phantom to study hemodynamics using MRI and cardiac catheterization in normal and aortic coarctation conditions.
Authors: Urbina, Jesús
Sotelo, Julio A
Springmüller, Daniel
Montalba, Cristian
Letelier, Karis
Tejos, Cristián
Irarrázaval, Pablo
Andia, Marcelo E
Razavi, Reza
Valverde, Israel
Uribe, Sergio A
Keywords: 3D PC-MRI;aortic coarctation;aortic phantom;catheterization;hemodynamic parameters
metadata.dc.subject.mesh: Aorta
Aortic Coarctation
Blood Flow Velocity
Cardiac Catheterization
Cardiac Imaging Techniques
Equipment Design
Equipment Failure Analysis
Magnetic Resonance Angiography
Phantoms, Imaging
Reproducibility of Results
Sensitivity and Specificity
Issue Date: 10-Mar-2016
Abstract: To design and characterize a magnetic resonance imaging (MRI)-compatible aortic phantom simulating normal and aortic coarctation (AoCo) conditions and to compare its hemodynamics with healthy volunteers and AoCo patients. The phantom is composed of an MRI-compatible pump, control unit, aortic model, compliance chamber, nonreturn, and shutoff valves. The phantom without and with AoCo (13, 11, and 9 mm) was studied using 2D and 3D phase-contrast data and with a catheterization unit to measure pressures. The phantom data were compared with the mean values of 10 healthy volunteers and two AoCo patients. Hemodynamic parameters in the normal phantom and healthy volunteers were: heart rate: 68/61 bpm, cardiac output: 3.5/4.5 L/min, peak flow and peak velocity (Vpeak) in the ascending aorta (AAo): 270/357 mL/s (significantly, P We propose and characterize a normal and an AoCo phantom, whose hemodynamics, including velocity, flow, and pressure data are within the range of healthy volunteers and patients with AoCo. J. Magn. Reson. Imaging 2016;44:683-697.
metadata.dc.identifier.doi: 10.1002/jmri.25208
Appears in Collections:Producción 2020

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